Fantasy Football Week 2 Injury Updates Including Xavier Worthy And Drake London

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If you are not paying attention to our weekly injury report, then what are you doing? Football is a violent game, and players get hurt. Even if a player is active, any lingering injury will limit his effectiveness. That makes is extremely vital to be aware of all relevant injuries applicable to both your fantasy assets, and their depth chart counterparts. These are players to look into ahead of Week 2.
QUARTERBACKS
Brock Purdy - Luckily for fantasy managers, quarterbacks remain quite healthy this week. Brock Purdy is the only notable injury. His injury is with his non-throwing shoulder and new reports state that Brock Purdy will miss 2-5 weeks, thus elevating Mac Jones to the starting role.
49ers QB Brock Purdy will miss 2-5 weeks with a form of turf toe. (via @rapsheet) pic.twitter.com/CcuyQngF6H
— NFL (@NFL) September 11, 2025
RUNNING BACKS
Quinshon Judkins* - This is not an injury, but a notable start/sit decision. Will he play Week 2? Reports suggest that Quinshon Judkins will make his NFL debut this Sunday, but a fantasy football sit as his playing-time should be very limited.
Quinshon Judkins will “probably” debut Week 2 @ BAL, per @MaryKayCabot #DawgPound pic.twitter.com/2GflU7sz7T
— SleeperBrowns (@SleeperBrowns) September 6, 2025
Roschon Johnson - He looks to play in Week 2 dealing with a foot injury. He is not startable in fantasy football, but is handcuff value.
Will Shipley - Working with a rib injury, he is very likely to be out a little while. Boost to Tank Bigsby right off the bat. Bigsby is not startable this week, but a great handcuff stash.
WIDE RECEIVERS
Xavier Worthy - In a collision with Travis Kelce, Xavier Worthy dislocated his shoulder. As is common with dislocations, Worthy will not require surgery (although should get it in the offseason). Xavier Worthy is OUT Week 2. He is expected to play Week 3.
Drake London - Reports just came out that Drake London will play Week 2. This is huge for fantasy football managers.
Morris: Drake London expected to play Week 2. https://t.co/ogKu67z1HZ
— Underdog NFL (@UnderdogNFL) September 10, 2025
Jauan Jennings - The scans on Jauan Jennings shoulder came back clean, providing optimism that he will play in Week 2. Jauan Jennings is ACTIVE for today's game.
Christian Kirk - He is not yet ready to return from his hamstring injury. He will remain OUT in Week 2.
TIGHT ENDS
George Kittle - This is a massive blow to fantasy managers, as Kittle will miss at least four games on the IR. He is known for being injury prone with a vast history of soft-tissue injuries. Boost to Jauan Jennings (If Active), Ricky Pearsall, and Christian McCaffrey.
Brock Bowers - Fans held their breath on Sunday when Brock Bowers left the game with a knee injury, but he ended up being just fine. As of Saturday afternoon, Brock Bowers will be ACTIVE on Monday Night Football.
Isaiah Likely - He still awaits his NFL debut. With an ankle injury, Likely is still not practicing and will be OUT on Sunday. The team in hopeful for a Week 3 debut.
Dallas Goedert - He has been announced to have suffered a sprained knee in Week 1. This was not known until Wednesday. As of Friday afternoon, Dallas Goedert will be OUT on Sunday.
Mason Taylor - He is ACTIVE Week 2 (Ankle).
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Thomas Carelli is a sportswriter based on Northern New Jersey. He is a massive New York Jets and Mets fan, but that is not where is sports fandom stops. He loves to watch and play golf, all things football, baseball, and much more. If he can watch it, he will. Thomas graduated from William Paterson University in 2018 with a Bachelor's Degree in Sport Management. He spent 4 years working at a local golf course, volunteered past PGA events, and spent some part-time experience with the New York Jets events team. His passions for sport runs deep and his articles show for it.