The University of Texas says running back Malcolm Brown will miss this Saturday's game at home against eighth-ranked West Virginia game with sprained left ankle.
Brown left after the first quarter of the Longhorns' 41-36 victory over Oklahoma State last Saturday. He finished with three carries for seven yards.
Freshman tailback Johnathan Gray came on in relief and had 12 carries for 68 yards.
Brown, a sophomore, has 245 yards on 40 carries this season and three touchdowns.