Irsay bashed the Colts on Twitter on Monday, saying the team gave a "crap" performance and that his "commanders got an earful from me."
The team's starters played a few series and then gave way to the second and third-teamers. The result was 44-20 loss in which the team allowed 451 yards, turned the ball over three times and gave up a 107-yard kickoff-return touchdown by Bills rookie Marquise Goodwin.
"I think probably a combination of [mental and physical errors]," Colts coach Chuck Pagano said Monday. "You get a lot of young guys out there -- I don't mean it as an excuse -- but we made some mental errors and then, give [Buffalo] credit."