Shedeur Sanders Leads Cleveland Browns vs. Carolina Panthers: Odds, Predictions, How To Watch

How to watch Shedeur Sanders in his Browns vs. Panthers NFL Preseason game debut on Friday night.

Jul 26, 2025; Berea, OH, USA; Cleveland Browns quarterback Shedeur Sanders (12) celebrates with wide receiver Luke Floriea (37) during training camp at CrossCountry Mortgage Campus. Mandatory Credit: Ken Blaze-Imagn Images | Ken Blaze-Imagn Images

All eyes will be on former Jackson State quarterback Shedeur Sanders as he takes the helm for the Browns in Preseason Week 1. The 144th overall pick in the 2025 NFL Draft will have plenty to prove tonight against the Panthers.  

It's a crowded Cleveland quarterback room with NFL veterans Joe Flacco, Kenny Pickett, and rookies Dillon Gabriel and Shedeur Sanders battling for the top-three roster spots at the position.   

Shedeur may be "ice-skating uphill," as Louis Reddick mentioned last week, the young signal-caller is in an unfamiliar position. Never since his Pop Warner days has he had to wonder about starting at quarterback. His father, Coach Deion Sanders, has prepared him to face trials and tribulations, coming through them with tremendous success.

"We've already spoken three times today. We just got off the phone joking and clowning like crazy," Coach Prime said, then paused for a few seconds. "It's gonna be strange for both of us. I was in the hospital the last time I missed three games, but this time I'm well. Me going out there taking that walk and him taking that walk, and he knows I'm not there. That's different, that's different for him. He's so prepared right now. A lot of people are approaching it like a preseason game, but he's approaching it like 'A GAME!"  

Browns quarterback Shedeur Sanders throws as Dillon Gabriel looks on during training camp, Friday, Aug. 1, 2025, in Berea. | Jeff Lange / USA TODAY NETWORK via Imagn Images

Coach Sanders referenced cutting "the umbilical cord," while reflecting on his sons, Travis Hunter, and his other players who will debut in preseason games over the weekend. Shedeur and Coach Prime would have their pregame ritual of walking along the sidelines as his father would deliver his final instructions.   

I recall watching those walks. It gave me and many HBCU football fans chills when it occurred at Jackson State. Not because of the offensive onslaught waiting to be unleashed; however, it was because the love, respect, caring, and nurturing between a father and son within the Black community that made it special.  

“He’s gonna be a problem out there tonight,” - Coach Prime on Shedeur Sanders’ preseason debut 👀👀👀 pic.twitter.com/BBP4kDFNI4

— ESPN Cleveland (@ESPNCleveland) August 8, 2025

"I can't wait to see him get down tonight. It's gonna be a little weird. A little strange. I got to admit that. But, I'm praying for him and God has set him up and placed him in the perfect position he needs to be in." Coach Sanders closed, "He's gonna be a problem after tonight, I promise you that."

This evening in Carolina, Sanders will be alone, or maybe not. The Browns' leaders Joe Flacco and Myles Garrett have been extraordinarily protective and supportive as they reflected on Shedeur's time with the team.  

Browns quarterback Shedeur Sanders runs for a short gain during training camp, July 30, 2025, in Berea. | Jeff Lange / USA TODAY NETWORK via Imagn Images

Garrett stated, "He takes it seriously, his craft. He's watching what the others are doing. And, doing it his own way, which only he can. So, looking forward to seeing him in these preseason games... He looks good, but all the guys look good right now."

For him to get a chance to go out there and take the field...we're all gonna be on the sidelines and at home enjoying it," Flacco told reporters.

"He takes it seriously, his craft... He looks good."

Myles Garrett bares his confidence on Shedeur Sanders getting the start 🗣️

(via @Browns)pic.twitter.com/MMJyXs6g5w

— NFL on ClutchPoints (@ClutchPointsNFL) August 6, 2025

Nonetheless, HBCU football fans - whether fanatics about the Sanders family or just casual observers - Shedeur Sanders' start will be our event to watch. He's always had the confidence, swag, and mojo. His success will crush stereotypes and negative perceptions that exist in today's cultural climate.  

pic.twitter.com/PWF7MbiNmT

— Peggy Hagger (@PeggyHagger) August 5, 2025

Win or lose, it won't make or seal Sanders' professional fate, regardless, but hoping for a brilliant performance will be extremely exciting for us all. Especially satisfying for Sanders, his family, HBCU fans, and the Cleveland Browns faithful.

HOW TO WATCH

Where to watch the Cleveland Browns vs. Carolina Panthers in Week 1 of the 2025 NFL Preseason:

• Friday, August 8, 2025
• Time: 7 p.m. ET
• Venue: Bank of America Stadium
• Broadcast TV: NFL Network or YouTube NFL
• Browns record: 0-0
• Panthers record: 0-0

ODDS & PREDICTION

Neither Cleveland nor Carolina expects to play their veterans for an extended period on Friday night. Sanders and Huntley will serve as the Browns' quarterbacks for most of the game, with Sanders likely taking the lead in the first half. Huntley may come in during the second half to handle cleanup duties.

• DraftKings has the Panthers as a 4.5-point favorite
• HBCU Legends is going with the underdog, Cleveland by 2 points.
• Sanders will have over 140 yards of passing with one touchdown.
• Lead the Browns on two scoring drives.

Spread

• Browns +4.5 (-115)
• Panthers -4.5 (-105)

Moneyline

• Browns: +170
• Panthers: -205

Total

• 32.5 (Over -110/Under -110)

Odds refresh periodically and are subject to change. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.

Additional Shedeur Sanders articles:

Shedeur Sanders Is Primed & Ready For His NFL Preseason Debut

Former Jackson State Tigers star quarterback Shedeur Sanders will have a chance to seize the ultimate NFL preseason moment on Friday as he starts for the Cleveland Browns against the Carolina Panthers.  

This pivotal debut not only tests his skills—it places Sanders at the heart of enduring conversations about Black quarterbacks in the NFL, especially one with roots grounded in HBCU football.

The Legacy of Black Quarterbacks: From Doug Williams to Shedeur Sanders

"All he needs is an opportunity." Those were the immortal words of Eddie Robinson, who was advocating for Doug Williams before the 1978 NFL Draft. Thanks to a young and open-minded scout named Joe Gibbs, Williams may not have been taken in the first round by the Tampa Bay Buccaneers. Fortunately, the HBCU legend's entry paved the way for generations of Black quarterbacks to follow.   

Not a day goes by when Doug Williams isn't encountered by people, usually Black people, eager to share their memory of Super Bowl XXII. | Todd Pendleton / USA TODAY NETWORK

Black signal-callers like Patrick Mahomes, Jalen Hurts, Cam Newton, Russell Williams, Lamar Jackson, Jayden Daniels, and CJ Stroud owe a debt of gratitude to Williams, James "Shack" Harris, Marlin Briscoe, Warren Moon, Randall Cunningham, Michael Vick, and even Tennessee State's greatest, Eldridge Dickey.  

Now, forty-seven years after Williams arrived in the NFL, Shedeur Sanders stands poised to echo the historic journeys of others as he takes the field for the Cleveland Browns.  

Still, the conversation about the legitimacy of Black quarterbacks, which Williams helped spark, remains as relevant in the 2025 NFL preseason as it was in the past — more so for the HBCU quarterback who's been marginalized in recent years.

Browns quarterback Shedeur Sanders works with offensive coordinator Tommy Rees during rookie minicamp May 9, 2025, in Berea. | Jeff Lange / USA TODAY NETWORK via Imagn Images

Shedeur Sanders' Preseason Debut: Browns vs Panthers 2025

The anticipation surrounding Sanders and Browns' preseason opener is at a fever pitch, with fans zeroing in on the intrigue around the 144th draft pick.  

Cleveland Browns head coach Kevin Stefanski confirmed the report that Shedeur Sanders will make his official Browns preseason debut as the team's starting quarterback. However, he stayed clear about the stakes for the rookie, which many believe are high.

All eyes will be on Sanders, a position that his father, Deion Sanders, has prepared him for his entire life. Will this become one of the most-watched NFL preseason games of 2025?  

The buzz isn't just about a rookie start; it's about what Sanders' performance will mean for the Browns and the narratives around a franchise that desperately needs a leader at the position.

It's a familiar scenario for the young man. He took over the struggling Jackson State and Colorado football programs, immediately infusing confidence in the quarterback position, as well as the leadership necessary to maintain winning for his teams.

Part of the reason fans who aren't supportive of the Browns are watching and hoping for Sanders' success this preseason. One unspoken fact remains: if he delivers a subpar soliloquy, earning another chance will become an uphill battle in Cleveland.

Cleveland Browns quarterback Joe Flacco (15) and quarterback Shedeur Sanders (12) look downfield during NFL training camp at CrossCountry Mortgage Campus, Wednesday, July 30, 2025, in Berea, Ohio. | Jeff Lange / USA TODAY NETWORK via Imagn Images

NFL Preseason Storylines: Is Shedeur Sanders "Ice Skating Uphill"?

Momentum for Sanders built rapidly after yesterday's Cleveland Browns training camp update. Pundits and supporters are divided. Last week, ESPN analyst Louis Reddick described the situation bluntly on First Take: "[Shedeur Sanders] is ice skating uphill."

His words hint at a larger uncertainty within the Browns' quarterback depth chart and skepticism surrounding Sanders' long-term prospects with the team. Kicking off in NFL preseason Week 1 as a rookie quarterback is both a tremendous shot and a daunting test. One, he'll certainly embrace.

Preseason Predictions, Reactions, and What's at Stake

As the Browns' quarterback battles intensify, every snap by Sanders in the NFL preseason 2025 will be scrutinized:

• Sanders' supporters believe he can command the Browns quarterback depth chart and prove himself as the team's best signal-caller.
• Doubters, including some within the front office, see this opportunity as a final verdict on why he was passed over during the 2025 NFL Draft.

Cleveland Browns quarterback Shedeur Sanders (12) throws during NFL training camp at CrossCountry Mortgage Campus, Friday, Aug. 1, 2025, in Berea, Ohio. | Jeff Lange / USA TODAY NETWORK via Imagn Images

Former NFL quarterback Robert Griffin III captured the tension in a pair of tweets:

• "Shedeur Sanders is being set up to fail in Cleveland. But God's got him showing out even with limited reps.”
• "Shedeur Sanders is starting the Cleveland Browns' preseason opener against the Carolina Panthers after getting limited opportunities with the starters in camp and being 4th on the QB depth chart. MASSIVE opportunity for Shedeur and MUST WATCH TV."

Historical Parallels: Eldridge Dickey and Black Quarterbacks in NFL History

While Sanders carves his path, his story is connected to those who paved the way. Eldridge Dickey—the first Black quarterback selected in the first round of a professional football draft—entered the league in 1968, chosen ahead of Alabama's Ken Stabler.

Despite excelling over Stabler in training camp, Dickey's disappointing preseason led to a position change, ultimately cutting short what could have been a trailblazing NFL quarterback career.  

This history underscores the persistent high-stakes environment that Sanders now navigates.

Deion Sanders With Shedeur Sanders - 2022 SWAC Championship | Credit: Kyle Anthony Mosley, HBCU Legends

Browns Quarterback Depth Chart 2025: Where Does Shedeur Sanders Stand?

The pressure on NFL rookie quarterback starters is relentless, especially in the charged atmosphere of the Browns' preseason. In recent Cleveland Browns training sessions, Sanders completed 4-of-7 passes during joint practices with the Panthers.

At the same time, competitors like veteran Kenny Pickett (5/7, 2 TDs) and rookie Dillon Gabriel (7/8, 1 TD) have posted strong showings of their own. The battle for the top spot on the Browns quarterback depth chart in 2025 is fierce, and every rep could influence the team's direction.

Shedeur Sanders At Jackson State | Credit: Kyle Anthony Mosley, HBCU Legends

Final Exam Time: Shedeur Sanders' NFL Opportunity

As ESPN Radio's Harry Douglas succinctly put it:

“You've been doing quizzes—now it's the final exam.”

For Shedeur Sanders, Friday night's Browns vs Panthers preseason 2025 game is more than a professional debut—it's a powerful moment to challenge expectations and take command of his NFL rookie season narrative.  

Will Sanders rise and stun the football world, or will skeptics be justified? Regardless of the outcome, Shedeur's start will become a must-watch TV event. Right?

We shall see.

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