CeeDee Lamb, Mike Evans, And 3 Other NFL Week 3 Injury Updates

Breaking down some of the biggest injuries from week three of the NFL season.

Sep 4, 2025; Philadelphia, Pennsylvania, USA; Dallas Cowboys wide receiver CeeDee Lamb (88) warms up prior to the game against the Philadelphia Eagles at Lincoln Financial Field. | Bill Streicher-Imagn Images

There were some major injuries in week three of the NFL, which could have big implications in fantasy football. Here are five of the most notable injuries.

CeeDee Lamb

Sep 14, 2025; Arlington, Texas, USA; Dallas Cowboys wide receiver CeeDee Lamb (88) runs with the ball against the New York Giants during the second quarter at AT&T Stadium. | Kevin Jairaj-Imagn Images

CeeDee Lamb got hurt early in the first quarter with an ankle injury after a one-yard loss on a rush. Lamb up until that point did not log a reception or target. He tried to return, but took himself out after running a route and, hopping out the field of play with his ankle noticeably bothering him.

CeeDee Lamb

Left ankle sprain, likely medial

Sometimes the left MCL (knee) is injured here as well.

This is a very strong (deltoid) ligament, so usually it takes a lot to injure this.

I expect them to tape this up and him to try to play through this. pic.twitter.com/HjnjSx0T9n

— Jesse Morse, M.D. (@DrJesseMorse) September 21, 2025

He eventually was ruled out for the rest of the game. The diagnosis and significance of the injury are still pretty unknown. With him being out, George Pickens becomes a premier fantasy WR, and Dallas TE Jake Ferguson will likely see a noticeable boost as well in his production.

Jauan Jennings

Sep 14, 2025; New Orleans, Louisiana, USA; San Francisco 49ers wide receiver Jauan Jennings (15) reacts to scoring a touchdown against the New Orleans Saints during the second half at Caesars Superdome. | Stephen Lew-Imagn Images

San Francisco 49ers wide receiver Jauan Jennings was officially ruled out ahead of Sunday’s contest  against the Arizona Cardinals.

He was ruled out with shoulder and ankle issues. He suffered a shoulder injury in week one and picked up ankle problems in week two. His return to action remains unknown, but a hopeful note is that he was listed as questionable going into the game. 49ers QB Brock Purdy was also ruled out in this contest against the Cardinals.

Colston Loveland

Aug 22, 2025; Kansas City, Missouri, USA; Chicago Bears tight end Colston Loveland (84) runs with the ball against Kansas City Chiefs safety Jaden Hicks (21) during the first half at GEHA Field at Arrowhead Stadium. | Jay Biggerstaff-Imagn Images

Colston Loveland has been pretty quiet in his rookie season, but he started his week three performance against the Dallas Cowboys with a huge play. Bears quarterback Caleb Williams connected with him for a 31-yard reception down the right sideline, early in the first quarter. The catch was Loveland’s longest reception of the season, but unfortunately, it ended up being his only catch of the game.

Loveland exited the game with a hip injury in the second quarter , and after being listed as questionable to return, was later listed as doubtful to return. The fact that he was not immediately listed as out following being questionable is at least encouraging. With him being out, Cole Kmet will see a rise in fantasy value. As far as how it could affect other Chicago pass catchers' fantasy values leans to not being significant, given Loveland's low production through the first two weeks of the season.

Mike Evans

Sep 21, 2025; Tampa, Florida, USA; Tampa Bay Buccaneers wide receiver Mike Evans (13) warms up before a game against the New York Jets at Raymond James Stadium. | Nathan Ray Seebeck-Imagn Images

Late in the fourth quarter, Tampa Bay Buccaneers wide receiver Mike Evans exited the game with a hamstring injury against the New York Jets. He did not return to the contest upon exiting, and it was announced that Evans will undergo an MRI to evaluate the significance of his injury.

#Buccaneers Mike Evans - hamstring injury. His history + age makes this riskier.

The reaction of throwing the helmet suggests he knows we’re looking at missed time pic.twitter.com/KwRdEmPS8w

— Deepak Chona, MD. SMA (@SportMDAnalysis) September 21, 2025

Prior to exiting, Evans had four receptions for 33 yards, and he secured his first touchdown of the season. With him potentially being out of the picture, all Buccaneers pass catchers could see a rise in volume. Through three weeks, Evans has had a total of 27 targets.

Terry McLaurin

Sep 21, 2025; Landover, Maryland, USA; Washington Commanders wide receiver Terry McLaurin (17) runs the ball during the second half as Las Vegas Raiders safety Isaiah Pola-Mao (20) defends at Northwest Stadium. | Amber Searls-Imagn Images

The Washington Commanders' WR1, Terry McLaurin, exited his team’s week three bout against the Las Vegas Raiders late with a quad injury.

When he left the game, the Commanders were already ahead by three touchdowns. So, pushing to go back in seemed like an unlikely choice even if he could play. As of now, there is no news on the significance of his injury in the game.