Betting Oddsmakers Unmoved by Matthew Stafford's Back Injury

Los Angeles Rams quarterback Matthew Stafford has been dealing with a back injury that has sidelined him at training camp, but it appears that he and the team are planning on him being ready for Week 1 of the regular season against the Houston Texans.

If Stafford is unable to go, NFL insider Ian Rapoport reported that the team loves backup Jimmy Garoppolo, who has a ton of starting experience in his NFL career.

The #Rams remain confident that Matthew Stafford will be ready to begin the regular season. But as was clear during yesterday’s joint practice with the #Cowboys, they love what Jimmy Garoppolo brings as his backup. https://t.co/Mowz2h6Zv0
— Ian Rapoport (@RapSheet) August 6, 2025

Stafford signed a new deal with the Rams in the offseason, and he's fresh off of a strong 2024 season where he led the Rams to the divisional round of the playoffs in the NFC. Stafford finished the regular season with 3,762 passing yards, 20 touchdowns and just eight picks in 16 games.

Even with Stafford banged up, the best betting sites for the NFL are expecting him to be ready to go in the regular season.

Los Angeles has a tough Week 1 matchup with the Houston Texans, but oddsmakers have left the Rams as favorites (by three points) despite all of the injury noise surrounding the Super Bowl champion quarterback.

Texans vs. Rams Odds, Spread and Total for NFL Week 1

Odds via DraftKings Sportsbook

Spread

Texans +3 (-110)
Rams -3 (-110)

Moneyline

Texans: +130
Rams: -155

Total

45.5 (Over -110/Under -110)

If these odds start to move in favor of Houston, it could be a sign that the betting market expects Stafford to miss the game. The Rams quarterback only played in nine games in the 2022 season, but he's played in 15 or more games in the regular season in his three other campaigns in Los Angeles.

Odds refresh periodically and are subject to change.

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