Joe Mixon 2025 Fantasy Football Outlook, Profile, Predictions

Joe Mixon delivered elite fantasy production for most of the 2024 season before injuries and a late-season offensive slump limited his overall impact. How will he fare in 2025?
Houston Texans running back Joe Mixon (28) reacts to his rushing first down against the Los Angeles Chargers in the fourth quarter in an AFC wild card game at NRG Stadium.
Houston Texans running back Joe Mixon (28) reacts to his rushing first down against the Los Angeles Chargers in the fourth quarter in an AFC wild card game at NRG Stadium. | Thomas Shea-Imagn Images

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Joe Mixon started the 2024 season as one of the most productive running backs in fantasy football before injuries and a fading Texans offense slowed his momentum. Despite a rough finish, he delivered elite value for much of the year and still outpaced several top-tier backs in total PPR scoring.

Joe Mixon, Houston Texans

Based on his play in eight of his first 10 games, Mixon should have ranked in the elite tier of running backs changing teams last season. He busted out of the gate with an impact showing (30/159/1 with three catches for 19 yards) but left Week 2 with an ankle issue, costing him the following three matchups.

The Texans worked him hard over his next eight games (23.4 touches per game), leading to six games with over 100 yards rushing and 11 touches). He scored over 25.00 fantasy points in four games on the year, highlighted his success in Week 7 (13/102/1 with two catches for 30 yards and a score), Week 7 (25/115/2 with two catches for nine yards), and Week 11 (20/109/3 with two catches for 44 yards). 

After his bye week, Mixon and Houston’s offense lost momentum. Mixon crushed fantasy teams over his final four starts (40/129 – 3.2 yards per rush with nine catches for 65 yards) while still having some ankle issues. In the playoffs, he posted two steady outcomes – 25/106/1 with one catch for 13 yards and 18/88/1 with two catches for 12 yards.

Mixon was a very attractive and winning running back for 11 weeks (57.9%) of his 19 possible games. His three missed games due to injuries and the demise of the Texan’s offense due to wide receiver injuries led to him not leading fantasy teams to better success late in the year. He played two fewer games than Aaron Jones but outscored him by over 20.00 fantasy points in PPR leagues. 

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Shawn Childs
SHAWN CHILDS

With 20+ years of experience in the high-stakes fantasy market, I aim to research and compete at the highest level in baseball and football each season. I've contributed as a writer/analyst for Sports Draft Daily, ScoutPro, Scout Fantasy, Fulltime Fantasy, FFToolbox, and Sports Illustrated Fantasy. I'm honored to be in the National Fantasy Baseball Championship Hall of Fame. My drafting philosophy is risk-averse yet open to betting on potential game-changers. I approach player selection with a neutral perspective, acknowledging that fantasy sports are inherently unpredictable due to injuries, performance dips, and managerial decisions. My work focuses on these main areas: - Season-long fantasy baseball and football - BestBall Baseball and Football Events - Daily Fantasy Sports (DFS): DraftKings, FanDuel, and Underdog - Long Shot Player Prop Parlays for NFL I participate in various leagues and contests, including NFBC, NFFC, RTSports, FFPC, DraftKings, Underdog Fantasy, FanDuel, and FFWC, with the goal of leveraging my extensive experience and research for success in each game format. A fantasy follower can expect in-depth profiles of NFL and MLB players, along with season-long and weekly projections for each fantasy football season. In addition, I have many strategy articles to help develop fantasy players' learning curves.

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