ACC Releases Final Injury Report for Louisville vs. Pitt

The Cardinals kick off against the Panthers at noon.

Aug 30, 2025; Louisville, Kentucky, USA; Louisville Cardinals running back Isaac Brown (1) runs the ball against Eastern Kentucky Colonels linebacker Kaden Smith (24) during the first half at L&N Federal Credit Union Stadium. Mandatory Credit: Jamie Rhodes-Imagn Images | Jamie Rhodes-Imagn Images

PITTSBURGH - It's finally game day in the Steel City. In just a couple hours, the Louisville football program is set to play their first matchup against a power conference foe this season, taking on Pitt in the ACC opener for both teams. Kickoff is set for 12:00 p.m. EST from Acrisure Stadium.

It's a matchup in which both sides are dealing with a handful of injuries. Two hours before kickoff, we learned just who will actually be able to suit up for both the Cardinals and Panthers, with the ACC releasing their third and final availability report.

On the Cardinals' side of things, star running back Isaac Brown as well as his backup Duke Watson, are both listed as "game time decisions." Both Brown and Watson had been listed as "questionable" in previous two availability reports.

However, per ESPN's Pete Thamel, it's expected that both will play against that Panthers. Thamel reports that Brown and Watson were "limited in practice this week" with lower-leg injuries.

Defensive linemen Wesley Bailey and Rene Konga, as well as linebacker Antonio Watts, were all listed as game time decisions as well. Like Brown and Watson, all three defensive players were questionable on the first two reports.

For the Panthers, they will be without their best player, as all-purpose back Desmond Reid was listed as "out" for the matchup. Reid had previously been listed as "questionable" on the first two availability report.

Below is the full report for both sides:

ACC's Game Day Availability Report for Louisville at Pitt

Louisville Cardinals

OUT

• LB #6 Stanquan Clark
• DB #7 Rodney Johnson
• QB #17 Travis Egan
• RB #22 Keyjuan Brown
• RB #33 Jamarice Wilder
• RB #43 Shammai Gates

GAME TIME DECISION

• RB #1 Isaac Brown
• LB #9 Antonio Watts
• DL #23 Wesley Bailey
• RB #26 Duke Watson
• DL #90 Rene Konga

Pitt Panthers

OUT

• RB #0 Desmond Reid
• DB #18 Rashan Murray
• LB #19 Jayden Bonsu
• RB #20 Synkwan Smith
• RB #27 Jaylin Brown
• LB #32 Jeremiah Marcelin
• RB #34 Derrick Davis Jr.
• TE #44 Adam Howanitz
• DL #50 Denim Cook
• DL #56 Jaeden Moore

GAME TIME DECISION

• DB #8 Tamon Lynum

(Photo of Isaac Brown: Jamie Rhodes - Imagn Images)

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