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Mar 12, 2026; Charlotte, NC, USA; Louisville Cardinals guard Adrian Wooley (14) with the ball as Miami (FL) Hurricanes guard Dante Allen (35) defends in the first half at Spectrum Center. Mandatory Credit: Bob Donnan-Imagn Images

Here are the three main ways that the Cardinals can take down the Bulls to start their run in the Big Dance.

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Here are the three main ways that the Cardinals can take down the Bulls to start their run in the Big Dance.

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Apr 8, 2013; Atlanta, GA, USA; Louisville Cardinals guard Peyton Siva (center) holds the trophy after Louisville won the championship game in the 2013 NCAA mens Final Four against the Michigan Wolverines at the Georgia Dome. Louisville Cardinals won 82-76. Mandatory Credit: Bob Donnan-Imagn Images

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The Cardinals have a rich history of success in the Big Dance.

Mar 12, 2026; Charlotte, NC, USA; Louisville Cardinals head coach Pat Kelsey reacts in the second half at Spectrum Center. Mandatory Credit: Bob Donnan-Imagn Images

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The Cardinals earned a No. 6 seed for the NCAA Tournament, and will face South Florida to get their run started.

Feb 23, 2026; Chapel Hill, North Carolina, USA; Louisville Cardinals guard Mikel Brown Jr. (0) with the ball in the first half at Dean E. Smith Center. Mandatory Credit: Bob Donnan-Imagn Images

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The star point guard for Louisville has missed the last four games due to his lingering lower back injury.

Mar 11, 2026; Charlotte, NC, USA; Louisville Cardinals mascot performs in the first half at Spectrum Center. Mandatory Credit: Bob Donnan-Imagn Images

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Follow along throughout the tournament as the Cardinals attempt to go on a run in the Big Dance.

Feb 21, 2026; Louisville, Kentucky, USA; Louisville Cardinals guard J'vonne Hadley (1) reacts during the first half against the Georgia Tech Yellow Jackets at KFC Yum! Center. Mandatory Credit: Jamie Rhodes-Imagn Images

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The Cardinals will get their run in the NCAA Tournament started with a matchup against the Bulls in Buffalo.

Mar 7, 2026; Duluth, GA, USA; Louisville Cardinals guard Tajianna Roberts (22) dribbles against the North Carolina Tar Heels in the third quarter at Gas South Arena. Mandatory Credit: Brett Davis-Imagn Images

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The Cardinals will face the Catamounts at the KFC Yum! Center to start their run in the Big Dance.

Mar 12, 2026; Charlotte, NC, USA; Louisville Cardinals guard Ryan Conwell (3) with the ball in the first half at Spectrum Center. Mandatory Credit: Bob Donnan-Imagn Images

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The Cardinals will gets their run in the Big Dance started against the Bulls.

Louisville Cardinals guard Mikel Brown Jr. (0) drives to the basket as the Louisville Cardinals host the Georgia Tech Yellow Jackets in an NCAA basketball game at the KFC Yum! Center, Saturday, Feb. 21, 2026, in Louisville.

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Selection Sunday is finally here, so we’re taking one last look at the Cardinals’ outlook for the Big Dance.

Feb 5, 2026; Louisville, Kentucky, USA; Louisville Cardinals guard Reyna Scott (1) talks with head coach Jeff Walz during the second half against the Duke Blue Devils at KFC Yum! Center. Duke defeated Louisville 59-58. Mandatory Credit: Jamie Rhodes-Imagn Images

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The Cardinals will host their first game in the Big Dance for the first time in four seasons.

Mar 6, 2026; Duluth, GA, USA; Louisville Cardinals head coach Jeff Walz talks to guard Imari Berry (2) during the game against the Syracuse Orange during the second half at Gas South Arena. Mandatory Credit: Dale Zanine-Imagn Images

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Selection Sunday is just two days away for the Cardinals.

The Louisville Cardinal mascot flexes before the game against South Carolina State at the KFC Yum! Center Monday night, Nov. 3, 2025.

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The Cardinals head into Selection Sunday as a stone cold lock to make the Big Dance.

Mar 12, 2026; Charlotte, NC, USA; Louisville Cardinals guard Ryan Conwell (3) handles the ball against Miami (FL) Hurricanes guard Dante Allen (35) during the second half at Spectrum Center. Mandatory Credit: Jim Dedmon-Imagn Images

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The Cardinals took down the Mustangs in the second round, but fell to the Hurricanes in the quarterfinals.

Mar 12, 2026; Charlotte, NC, USA; Louisville Cardinals guard Adrian Wooley (14) with the ball as Miami (FL) Hurricanes forward Timotej Malovec (88) defends in the first half at Spectrum Center. Mandatory Credit: Bob Donnan-Imagn Images

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The highlights plus team & player notes from the Cardinals' loss to the Hurricanes.

Mar 12, 2026; Charlotte, NC, USA; Louisville Cardinals head coach Pat Kelsey reacts in the first half at Spectrum Center. Mandatory Credit: Bob Donnan-Imagn Images

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Listen to what the head coach of the Cardinals and various payers said after their loss to the Hurricanes:

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The Cardinals' time in Charlotte has come to an end thanks to the Canes.

Spectrum Center in Charlotte, N.C. for the ACC Tournament

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The Cardinals and Hurricanes get a rematch in Charlotte less than a week removed from their regular season meeting.

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The Cardinals tip off against the Canes at 2:30 p.m. EST.

Feb 17, 2026; Dallas, Texas, USA; Louisville Cardinals guard Mikel Brown Jr. (0) looks on during the second half against the SMU Mustangs at Moody Coliseum. Mandatory Credit: Jerome Miron-Imagn Images

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The start point guard for Louisville was ruled out for the ACC Tournament due to his lingering lower back injury.

Mar 7, 2026; Coral Gables, Florida, USA; Miami Hurricanes guard Tru Washington (10) dribbles the ball against Louisville Cardinals guard J'vonne Hadley (1) during the second half at Watsco Center. Mandatory Credit: Jeff Romance-Imagn Images

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Less than a week removed from their regular season meeting, the Cardinals and Hurricanes square off in the conference tournament quarterfinals.

Mar 7, 2026; Coral Gables, Florida, USA; Louisville Cardinals forward Sananda Fru (13) battles for a loose ball against Miami Hurricanes forward Shelton Henderson (7) at Watsco Center. Mandatory Credit: Jeff Romance-Imagn Images

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Take a look at how the Cardinals stack up against the Hurricanes for their ACC Tournament matchup, and who the statistical models favor:

Mar 7, 2026; Coral Gables, Florida, USA; Louisville Cardinals guard Ryan Conwell (3) dribbles the ball against Miami Hurricanes forward Shelton Henderson (7) at Watsco Center. Mandatory Credit: Jeff Romance-Imagn Images

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The Cardinals get another crack at the Hurricanes after advancing to the quarters of the conference tournament.

Mar 11, 2026; Charlotte, NC, USA; Louisville Cardinals guard Ryan Conwell (3) reacts late in the second half at Spectrum Center. Mandatory Credit: Bob Donnan-Imagn Images

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The highlights, photo gallery plus team & player notes from the Cardinals' win over the Mustangs.

Mar 11, 2026; Charlotte, NC, USA; Louisville Cardinals head coach Pat Kelsey reacts in the first half at Spectrum Center. Mandatory Credit: Bob Donnan-Imagn Images

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Listen to what the head coach of the Cardinals and various payers said after their win over the Mustangs in the ACC Tournament:

Mar 11, 2026; Charlotte, NC, USA; Louisville Cardinals center Aly Khalifa (15) shoots against the Southern Methodist University Mustangs during the first half at Spectrum Center. Mandatory Credit: Jim Dedmon-Imagn Images

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The Cardinals got clutch plays in the final minute to take down the Mustangs and advance to the quarterfinals.