Mizzou's Sam Horn Exits Week 1 Game with Injury

The redshirt junior is in competition with Penn State transfer Beau Pribula to be Missouri's starting quarterback.

Aug 6, 2025; Columbia, MO, USA; Missouri Tigers quarterback Sam Horn (21) prepares for a drill during fall camp at Mizzou Athletics Training Complex. | Amber Winkler/MissouriOnSI

Quarterback Sam Horn left the Missouri Tigers' Week 1 game against Central Arkansas on Thursday night, exiting the field to the locker room after taking a hit to the knees on the Tigers' second drive of the game. He was seen in Missouri's locker room in crutches and a brace watching the game.

Update: #Mizzou QB Sam Horn was spotted in a full leg cast in the tunnel.

He was hit low on a 6-yard rush in the first half, went to the tent, then limped to the locker room. He did not return to the sideline before halftime. pic.twitter.com/19TFmpRhQy

— Zach Sweet (@ByZachSweet) August 29, 2025

Horn was one of two options Missouri was considering to be its starting quarterback entering the season. He was supposed to play in the entirety of the second half, following Penn State transfer Beau Pribula in the first half.

Horn subbed in on a play in the first quarter to take a designed quarterback run, but stayed on the field afterward to be evaluated by trainers. He walked off the field with the help of trainers into the medical tent. After a short time in the tent, he walked off with trainers into the locker room.

Horn is set to be examined for the injury Friday, head coach Eli Drinkwitz revealed after the game.

"Very disappointed and sad with the injury of Sam," Drinkwitz said after the game.