Rey Mysterio Suffers Injury On WWE WrestleMania SmackDown

Rey Mysterio is scheduled to face El Grande Americano Saturday night at WrestleMania 41, but that match may now be in question.
The WWE Hall of Famer was competing in a six-man tag team match Friday night on SmackDown and suffered an injury at some point during the bout.
Mysterio was tended to by the WWE medical team for several minutes while Rey Fenix and Dragon Lee went on to defeat American Made without him.
Rey Mysterio needed help getting back to the locker room after the tag team match on #Smackdown.
— James H. Williams | USA Today (@JHWreporter) April 19, 2025
Rey’s #WrestleMania match with El Grande Americano could be in jeopardy.
Read: https://t.co/MRQHirIlvN https://t.co/kPp0x7rlBh pic.twitter.com/eQrtaItGGC
After the match, as was captured on video above by USA Today, Rey Mysterio needed assistance to walk back up the ramp and was noticeably struggling to put weight on his left leg.
It's way too soon to know what kind of an impact this will have on his scheduled match tomorrow night with the man many assume to be Chad Gable.
We'll provide an update on Mysterio's injury as soon as one becomes available.
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Rick Ucchino is the Assistant Editor & Content Coordinator for The Takedown on SI. He also works full-time for 700WLW Radio in Cincinnati, Ohio as a local news and sports anchor, in addition to his time covering the Cincinnati Bengals for Sirius XM. Rick has been on the professional wrestling beat since 2019, having provided coverage for a number of outlets, including Fightful, SB Nation’s Cageside Seats and the Bleav Podcast Network. With an educational background in theater, creative writing and journalism, Rick focuses primarily on the storytelling aspect of pro wrestling, but he’s no stranger to the squared circle himself. He had the privilege of training with former WWE & WCW cruiserweight Jimmy Wang Yang for nearly two years and retired early due to back issues with a perfect 1-0 record in singles competition. Rick is a married father of two incredibly adorable children, who are budding pro wrestling fans themselves. Much to the chagrin of their mother. You can reach Rick at rwucchino@gmail.com