Omarion Hampton and Brock Bowers Among Key NFL Players on Week 6 Injury Report

Omarion Hampton, Brock Bowers, and many others continue to affect your fantasy football rosters ahead of NFL Week 6.
Sep 21, 2025; Inglewood, California, USA;  Los Angeles Chargers running back Omarion Hampton (8) leaves the field after defeating the Denver Broncos 23-20 at SoFi Stadium. Mandatory Credit: Jayne Kamin-Oncea-Imagn Images
Sep 21, 2025; Inglewood, California, USA; Los Angeles Chargers running back Omarion Hampton (8) leaves the field after defeating the Denver Broncos 23-20 at SoFi Stadium. Mandatory Credit: Jayne Kamin-Oncea-Imagn Images | Jayne Kamin-Oncea-Imagn Images

Week 5 came and went but, luckily, it did not claim as many injury victims as we have seen in the past. The one major concern that we saw was with Omarion Hampton, who will now be out 4 weeks on the IR. Beyond him, it appears all injuries are minor as we are currently being told. Even though the injury report may be light for now, we all know that it can change in a whim. For that reason, it is important to stay tuned in to our weekly injury report.

QUARTERBACKS

Lamar Jackson

He has been slated to return in Week 8. Optimism had been up in the air that he could play this week, but Jackson will remain out past the Week 7 bye.

JJ McCarthy

McCarthy is rehabbing well and is slated to return in Week 7, post-bye week.

Brock Purdy

Purdy will be OUT Sunday. Mac Jones will start.

Kyler Murray

He suffered a foot injury in Week 5. Murray will be OUT. Jacoby Brissett starts but is not fantasy viable.

Tua Tagoliavoa

He was limited in Wednesday practice (hip/thumb). He should play, but we will stay tuned in. Tua practiced in full on Thursday and will play.


RUNNING BACKS

Saquon Barkley

The star running back is being limited in practice with soreness. He is not expected to miss any playing time. He will play Thursday.

Omarion Hampton

His injury is listed as an ankle, but there are lacking reports on the specifics. Hampton will be out 4 weeks as he was placed on the IR. Speculation suggests that he has a bruise or strain, but nothing too major.

Jaylen Warren

His status remains unconfirmed, but speculated probable to play.

Chuba Hubbard

Hubbard will be out for the 2nd week in a row. Dowdle starts.

Bucky Irving

Bucky remains out in Week 6. Plan for Rachaad White.

Alvin Kamara

Kamara injured his ankle in Wednesday practice, but is expected to play without it being an issue.


WIDE RECEIVERS

Darius Slayton

Slayton is going to be out for Thursday Night Football with a hamstring injury. This Giants offense takes another huge hit. Wan'Dale Robinson and Jalin Hyatt get upgrades, as well as Theo Johnson. They are spread very thin.

Terry McLaurin

McLaurin had cautious optimism all week that he might play. It looks that he will be OUT.

Jalen Coker

His 21-day practice window has been opened, but do not expect him back in Week 6.

CeeDee Lamb

He will not yet return in Week 6. The team expects him to be back within two weeks. This raises optimism for Week 7 and probable status of Week 8.

Jauan Jennings

The 49ers had a huge win without Jennings and Pearsall. He will play.

Ricky Pearsall

Kendrick Bourne really stepped up in Week 5. He will have to do so as Pearsall will be out again.

Darnell Mooney

Mooney was expected to return but he missed Friday practice. He will be OUT, providing a massive boost to London.

Zay Flowers

He is officially questionable with a shoulder injury. The Ravens have said he will be active in limited fashion.

Chris Godwin

He is back on the injury report, this time with a fibula (leg) issue. He will not go on the IR, but he will be out with multi-week risk.

Quentin Johnston

He will NOT PLAY with a hamstring injury.

Amon-Ra St. Brown

It sounds likely that he will play, but St. Brown popped up with a wrist injury worth paying attention to. He was back as a full-participant on Thursday.

Xavier Worthy

He popped back up the Thursday injury report and came right back off of it on Friday. He will play.

Ja'Marr Chase

He has an illness and was sent home following team walkthroughs. Chase will be play, but is clearly still sick.


TIGHT ENDS

Brenton Strange

He has been placed on the IR with a quad injury. Strange has been vital to the team rushing success, so this is a big hit to the offense. Hunter Long will be a serviceable replacement in the meantime.

Brock Bowers

He is week-to-week. The team wants him to get back healthy. Bowers will be OUT this week.

Juwan Johnson

He is being limited to an ankle injury. Stay tuned for a full status.

Dalton Kincaid

Kincaid has an oblique injury but will have one extra day for Monday Night Football.

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Thomas Carelli
THOMAS CARELLI

Thomas Carelli is a sportswriter based on Northern New Jersey. He is a massive New York Jets and Mets fan, but that is not where is sports fandom stops. He loves to watch and play golf, all things football, baseball, and much more. If he can watch it, he will. Thomas graduated from William Paterson University in 2018 with a Bachelor's Degree in Sport Management. He spent 4 years working at a local golf course, volunteered past PGA events, and spent some part-time experience with the New York Jets events team. His passions for sport runs deep and his articles show for it.