Spread & Over/Under Predictions for West Virginia vs. Houston

Picks for this week's game between the Mountaineers and Cougars.
West Virginia University receiver Cam Vaughn
West Virginia University receiver Cam Vaughn | Christopher Hall – West Virginia on SI

Hitting the road once again for what seems like the 18th road trip this season for West Virginia, and this will be their most difficult opponent away from home so far, facing the 22nd-ranked Houston Cougars.

Can WVU get the job done or at least keep it close?

Spread: Houston - 13.5

Joe Rondone/The Republic / USA TODAY NETWORK via Imagn Images
Houston Cougars quarterback Conner Weigman (1) scrambles with the ball as they play against the ASU Sun Devils at Mountain America Stadium in Tempe on Oct. 25, 2025. | Joe Rondone/The Republic / USA TODAY NETWORK via Imagn Images

Prediction: Houston covers.

I'm torn on this, to be completely honest with you. If West Virginia's defense plays like it did a week ago and Scotty Fox plays another clean game at quarterback and moves the ball, the Mountaineers will have a chance to not only cover but also win this game.

However, the road has not treated the Mountaineers kindly this season, and it's hard for me to believe that their luck will change this week against a pretty stingy defense with a true freshman at quarterback. Fox did a great job of taking what a poor TCU pass defense gave him and made them pay. Houston will allow him to complete passes underneath, but they now have a full game of tape on him and will know exactly how to get after him and force him into bad decisions. The lack of a run game will also hurt WVU in this one. WVU hangs around, but the Cougars ultimately pull away.

Total: 49.5

Ben Queen-Imagn Images
Oct 25, 2025; Morgantown, West Virginia, USA; Texas Christian University Horned Frogs wide receiver Eric McAlister (1) is tackled by many West Virginia Mountaineers defenders during the first quarter at Milan Puskar Stadium. Mandatory Credit: Ben Queen-Imagn Images | Ben Queen-Imagn Images

Prediction: Under

West Virginia's defense flew around and played its best game in Big 12 Conference play last week against an explosive TCU offense. That should give them some confidence to carry that over into this week's matchup against Houston, which has not found a ton of success on the ground and isn't going to necessarily light you up through the air.

I also have a feeling we're going to see a few freshman moments from Scotty Fox in this game, and if it results in turnovers and a bunch of three-and-outs, they'll revert to their pre-TCU ways.

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Schuyler Callihan
SCHUYLER CALLIHAN

Schuyler Callihan is the publisher of West Virginia On SI and has been a trusted source covering the Mountaineers since 2016. He is the host of Between The Eers, The Walk Thru Game Day Show, and In the Gun Podcast. The Wheeling, WV native moved to Charlotte, North Carolina in 2020 to cover the Charlotte Hornets and Carolina Panthers.

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