USC vs. Colorado odds, spread: Week 5 college football game betting picks

Early betting intel on USC vs. Colorado in this anticipated Week 5 college football game

USC vs. Colorado odds, lines

Courtesy of SI Sportsbook

Line: USC -21.5
Total: 74.5 (O -111, U -111)
ML: USC -2000 | CU +725
FPI pick: USC 89.7% to win (More)

Betting trends

+ USC is 2-4 ATS in its last 6 games

+ Colorado is 4-12 ATS in its last 16 games

+ Total went over in 11 of USC's last 12 games

+ Total went over in 11 of Colorado's last 15 games

+ Total went over in 5 of USC's last 6 road games

+ Buffaloes are 0-5 ATS in their last 5 Pac-12 games

Spread consensus pick

Colorado: 52 percent of bettors pick the Buffaloes at +21.5

USC: 48 percent of bettors side with the Trojans to cover

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USC vs. Colorado schedule

When: Sat., Sept. 30
Time: 10 a.m. MT, 9 a.m. PT
TV: Fox network
Stream live: fuboTV (Try for free)

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