2021 CIF Southern California Regional high school girls basketball playoff brackets: Matchups, scores, game times

The 2021 CIF Southern California Regional state playoff brackets have been released, and by the end of the week, 12 teams high school girls basketball teams will have been crowned as SoCal champions.
Mater Dei is the top seed in the Open Division after going undefeated through the CIFSS Open Division championship, and has earned a first-round bye. No. 2 Corona Centennial will take on No. 7 La Jolla Country Day in the first round.
First-round games in every division are scheduled to for Tuesday, June 15. The semifinals are scheduled for June 17 and the championship games are scheduled for June 19.
Check SBLive’s CIF SoCal Regional girls basketball brackets below for all the scores, game times and updated matchups:
CIF SOCAL REGIONAL GIRLS BASKETBALL BRACKETS

Lance Smith is a veteran high school sports reporter who worked previously with SBLive Sports covering basketball, football, and softball in California's Southern Section and LA City Section and has returned as contributor to High School On SI in 2025. He also covers Nevada and National Girls Basketball. A graduate of The USC Marshall School of Business, Smith dabbles in linear algebra and football and basketball computer rankings.