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ESPN College GameDay hosts make Week 1 college football game picks
Week 1 of the college football schedule is finally here as the rest of the nation kicks off for the first full Saturday slate of games in 2022.
There are several intriguing matchups on tap, including a few that will have some major early College Football Playoff implications.
What do the hosts at ESPN College GameDay predict for the Week 1 slate?
ESPN GameDay hosts make Week 1 college football picks
Notre Dame at Ohio State
Howard: Ohio State
Corso: Ohio State
College Football HQ pick: Ohio State by 10
More: Ohio State vs. Notre Dame football preview, prediction
North Carolina at Appalachian State
Howard: App State
Corso: North Carolina
Herbstreit: North Carolina
College Football HQ pick: North Carolina by 9
Houston at UTSA
Howard: Houston
Corso: Houston
Herbstreit: Houston
College Football HQ pick: Houston by 17
Boise State at Oregon State
Howard: Oregon State
Corso: Oregon State
Herbstreit: Oregon State
College Football HQ pick: Oregon State by 6
Louisville at Syracuse
Howard: Louisville
Corso: Syracuse
Herbstreit: Louisville
College Football HQ pick: Louisville by 13
Cincinnati at Arkansas
Howard: Arkansas
Corso: Arkansas
Herbstreit: Cincinnati
College Football HQ pick: Arkansas by 7
More: Arkansas vs. Cincinnati football preview, prediction
Utah at Florida
Howard: Utah
Corso: Utah
Herbstreit: Florida
College Football HQ pick: Florida by 2
More: Utah vs. Florida football preview, prediction
Oregon vs. Georgia
Howard: Georgia
Corso: Georgia
Herbstreit: Georgia
College Football HQ pick: Georgia by 14
More: Oregon vs. Georgia football preview, prediction
Florida State vs. LSU
Howard: Florida State
Corso: Florida State
Herbstreit: LSU
College Football HQ pick: LSU by 10
Clemson vs. Georgia Tech
Howard: Clemson
Corso: Clemson
Herbstreit: Clemson
College Football HQ pick: Clemson by 31
More: Clemson vs. Georgia Tech football preview, prediction
James Parks is the founder and publisher of College Football HQ. He has covered football for a decade, previously managing several team sites and publishing national content for 247Sports.com for five years. His work has also been published on CBSSports.com. He founded College Football HQ in 2020, and the site joined the Sports Illustrated Fannation Network in 2022 and the On SI network in 2024.