Lamar Jackson, Bucky Irving Among Major NFL Players on Week 5 Injury Report

Week 4 has been the worst week to date of key NFL injuries. We saw Malik Nabers, Tyreek Hill, and Lamar Jackson all go down with their own respective injuries. These hit fantasy football managers in notable fashion and so be sure to checkout our impact articles regarding how to handle these absences. As we enter Week 5, this is our injury report to assist you with waiver wire and start 'em, sit 'em decisions.

QUARTERBACKS

Lamar Jackson

He is not at practice on Wednesday, but he will be out 2-3 weeks, so be sure to hit the waiver wire in the meantime.

Jayden Daniels

Daniels is back on action and ready to start on Sunday.

Brock Purdy

Purdy has been listed OUT in Week 5. Once again, Mac Jones will be a very viable replacement.

JJ McCarthy

He looks to work further this week towards a return to the field, but is very unlikely to play in London.

Jaxson Dart

He seemed to injure his hamstring in Sunday's win, but Dart will be ACTIVE in Week 5.

Baker Mayfield

Baker has knee and arm injury, but he will start Week 5.

RUNNING BACKS

Trey Benson

The Cardinals took another hit with Benson. He will miss 4-6 weeks on an IR stint with a meniscus injury that had him undergo arthroscopic surgery.

Bucky Irving

Irving showed up this week in a walking boot and now will be OUT Week 5 and very likely Week 6.

Braelon Allen

He will be out 8-12 weeks with an MCL sprain.

Chuba Hubbard

Hubbard will be OUT in Week 5. Read more here.

Tyrone Tracy

He will be OUT today. Huge boost to Cam Skattebo.

WIDE RECEIVERS

Tyreek Hill

Hill dislocated his knee on Monday Night Football and is out for the season. His team is optimistic towards a 2026 return, but there will be a lot to fix with this huge injury.

Jauan Jennings

Jennings has a list of injuries that he is working through. He will be OUT Week 5.

Ricky Pearsall

Thursday Night Football is too short of a week for Pearsall to get healthy, so he will be OUT.

Cedric Tillman

Tillman hurt his hamstring in Week 4 and lands on the IR.

CeeDee Lamb

The team has shied away from putting Lamb on the IR. Despite trending upwards, he will still be very unlikely to play Week 5 at the Jets.

Brian Schottenheimer said they currently don’t have plans to put WR CeeDee Lamb (ankle) or RG Tyler Booker (ankle) on injured reserve. “Both are trending in the right direction. Both guys are getting better.” Booker is no longer wearing a walking boot
— Jon Machota (@jonmachota) September 29, 2025

Terry McLaurin

Initial reports would suggest him to not return in Week 5.

Malik Nabers

As you well know, he tore his ACL and is out for the season.

Darnell Mooney

Despite tweaking his hamstring, Mooney is expected to be back in Week 5.

Calvin Ridley

Ridley was really battling injury in Week 4. Perhaps he should not have played, but he will remain questionable for Week 5 with his undisclosed injury. Ridley is now expected to play.

Nico Collins

He was limited in Wednesday practice, but trends more likely than not to play this week.

Michael Pittman Jr

Pittman was added to the report Thursday with a hamstring injury. My liking to Josh Downs this week increases if Pittman is out. New reports have Pittman ACTIVE this week.

TIGHT ENDS

Brock Bowers

As of Saturday afternoon, it appears Bowers may turn out to miss Week 5. Stay tuned for confirmation, but it will be good for him to get to 100%.

Dallas Goedert

He has played fantastic football this season, but he has returned to the Week 5 injury report with a knee injury. Goedert returned to Thursday practice and will play.

Juwan Johnson

He was added to the Wednesday injury report as a no-go in practice. Stay tuned.

Darren Waller

It appears he missed Wednesday practice more for rest than his hip. He will play Week 5.

David Njoku

He was limited in practice but would appears likely to play.