Astros vs. Giants Prediction, Odds, Pick and Probable Pitchers for Wednesday, June 12

Breaking down odds, key players, and best bet for Wednesday's interleague game between the Houston Astros and San Francisco Giants.
May 21, 2024; Pittsburgh, Pennsylvania, USA;  San Francisco Giants starting pitcher Logan Webb (62) delivers a pitch against the Pittsburgh Pirates during the first inning at PNC Park. Mandatory Credit: Charles LeClaire-USA TODAY Sports
May 21, 2024; Pittsburgh, Pennsylvania, USA; San Francisco Giants starting pitcher Logan Webb (62) delivers a pitch against the Pittsburgh Pirates during the first inning at PNC Park. Mandatory Credit: Charles LeClaire-USA TODAY Sports / Charles LeClaire-USA TODAY Sports

The San Francisco Giants and Houston Astros will play in a rubber-match on Wednesday afternoon.

The Giants won the first game 4-3 and then the Astros evened up the series with a 3-1 win on Tuesday. Let's dive into everything we need to know to bet on today's Game 3 in this interleague showdown.

All odds listed in this article are via FanDuel Sportsbook

Astros vs. Giants Odds, Run Line, and Total

Spread

  • Astros -1.5 (+160)
  • Giants +1.5 (-194)

Moneyline

  • Astros +100
  • Giants -118

Total

  • 7 (Over -120/Under -102)

Astros vs. Giants Probable Pitchers

  • Houston: Framber Valdez (5-3, 3.53 ERA)
  • San Francisco: Logan Webb (5-5, 2.92 ERA)

Astros vs. Giants How to Watch

  • Date: Wednesday, June 12
  • Time: 3:45 p.m. EST
  • Venue: Oracle Park
  • How to watch (TV): NBCS-BA
  • Astros record: 31-37
  • Giants record: 33-35

Astros vs. Giants Key Players to Watch

Houston Astros

Jose Altuve: The Astros' second baseman has been quietly having a fantastic season, batting .295 while racking up 26 RBIs and 10 home runs. If anyone is going to find a way to get to Logan Webb and his 2.92 ERA, it's Altuve.

San Francisco Giants

Logan Webb: The Astros' offense has been hot of late so it's up to Logan Webb to slow them down. He's allowed more than two runs only once in his last six starts, so he needs to keep that trend up for the Giants to win this game.

Astros vs. Giants Prediction and Pick

Framber Valdez (3.53 ERA) gets the start for the Astros today which could work in favor of the Giants, who are eighth in the Majors in OPS against left-handed pitchers. Their OPS improves from .674 against right-handed pitchers to .739 against lefties.

If there's a time to bet on the Giants, it's when they take on a lefty like they do this afternoon.

Meanwhile, the Giants will be starting Logan Webb, who has been fantastic this season with a 2.92 ERA.

I'll back San Francisco as a slight home favorite.

Pick: Giants -118


Odds refresh periodically and are subject to change.

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Iain MacMillan
IAIN MACMILLAN

Originally from Nova Scotia, Iain MacMillan is a senior editor covering betting, with a focus on NFL, NHL, and golf. He hosts the Bacon Bets Podcast and has been featured on VSIN, BetQL and Monumental Sports Network. He is a member of the Metropolitan Golf Writers Association and his beloved Falcons and Maple Leafs break his heart on a yearly basis.