Red Sox vs. Phillies Prediction, Odds, Probable Pitchers and Prop Bets for Tuesday, July 22

Sean Treppedi | Jul 22, 2025

Kyle Schwarber has an optimal matchup against Red Sox pitching on Tuesday. / Bill Streicher-Imagn Images

The Philadelphia Phillies walked off the Boston Red Sox in bizarre fashion Monday night, earning a 3-2 win in the 10th inning on a catcher’s interference call. 

With the bases loaded and nobody out, Edmundo Sosa’s check swing clipped the glove of Boston catcher Carlos Narvaez. After a successful review by Philadelphia, the interference was confirmed, allowing Brandon Marsh to score the winning run — without the Phillies recording a hit in the inning.

Philly will follow up with Cristopher Sánchez (8-2, 2.50 ERA), who has quietly emerged as one of the most reliable arms in the Phillies’ rotation, on Tuesday. He's coming off a dominant 7.⅓-inning outing in San Diego where he allowed just one run and struck out six. 

Richard Fitts (1-3, 4.28 ERA) counters for Boston, and he is still finding his footing in his rookie season but showing promise in recent outings, including a win over Colorado where he allowed just two earned runs over 5 ⅔ innings. 

Red Sox vs. Phillies Odds, Run Line and Total

Odds via FanDuel Sportsbook

Run Line

• Red Sox +1.5 (-130)
• Phillies -1.5 (+108)

Moneyline

• Red Sox (+166)
• Phillies (-198)

Total

• Over 8.5 (-105)
• Under 8.5 (-115)

Red Sox vs. Phillies Probable Pitchers

• Red Sox: Richard Fitts (1-3, 4.28 ERA)
• Phillies: Christopher Sanchez (8-2, 2.50 ERA)

Red Sox vs. Phillies How to Watch

• Date: Tuesday, July 22, 2025
• Time: 6:45 p.m. ET
• Venue: Citizens Bank Park
• How to Watch (TV): NESN, NBCSP
• Red Sox Record: 54-48
• Phillies Record: 57-43

Red Sox vs. Phillies Prop Bet

• Kyle Schwarber Home Run (+235 at FanDuel)

Schwarber enters Tuesday’s game with 22 homers on the season and a long track record of thriving against right-handed pitching, especially at Citizens Bank Park. He’s likely to face rookie Richard Fitts, who’s allowing 1.3 homers per nine innings and making his first career appearance in this hitter-friendly environment. Schwarber, who often sets the tone as 

Philadelphia’s leadoff hitter, has elite barrel rates and ranks among the league leaders in average exit velocity. 

Fitts relies heavily on a four-seam fastball that Schwarber feasts on — he's slugging over .700 against that pitch this year. With Schwarber seeing the ball well lately and Fitts still adjusting to major league hitters, the power lefty is in a prime spot to go deep. 

Red Sox vs. Phillies Prediction and Pick

Despite Monday’s agonizing extra-inning loss, the Red Sox enter Tuesday’s matchup in strong form and offer real value on the moneyline. The public is fading Boston in this spot, but it is 12-4 in July and now sits in the final AL Wild Card spot, fueled by an offense averaging 5.5 runs per game this month with a wRC+ of 122. Their bats have stayed hot against left-handed pitching, ranking third in MLB with a 113 wRC+ on the season per FanGraphs — that makes them a serious threat to the lefty Sanchez.

Fitts has subtly rebounded from his early June disaster, stringing together three strong starts with a 3.55 ERA and a 25% strikeout rate per Statcast. His Stuff+ of 110 suggests the underlying tools are legit, and he’ll benefit from a Phillies lineup that has cooled off against right-handed pitching. The absence of Alec Bohm, one of the Phillies’ more consistent bats, only adds to the offensive question marks.While Sanchez has been stellar, the +165 price on Boston bakes in little respect for their current form or offensive edge. 

Pick: Red Sox (+165 at FanDuel)

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Odds refresh periodically and are subject to change.

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