Saints vs. Packers Prediction, Odds, Spread, Injuries, Trends for NFL Week 16

Can the Packers move to 4-2 against the spread as home favorites?

Peter Dewey | Dec 17, 2024

The Packers are massive favorites in Week 16. / Steven Bisig-Imagn Images

For the second straight week, the Green Bay Packers are in primetime, this time to take on the New Orleans Saints at Lambeau Field.

New Orleans still can make the playoffs, although NFL.com gives it less than a one percent chance to do so this season. And with Derek Carr dealing with a hand injury, it seems like their season is done.

New Orleans started Jake Haener in Week 15 before replacing him with Spencer Rattler, who played much better and nearly led the Saints to a comeback win over Washington. Instead, the Saints lost by one, and now they’re set as massive underdogs on Monday night – a sign that Carr once again won’t play.

Green Bay is 10-4 and holds the No. 6 seed in the NFC, but it is still in the mix for a higher seed depending upon how the Minnesota Vikings and Detroit Lions close out the season.

Here’s a breakdown of the odds, players to watch, betting trends, my prediction and more for Monday night’s NFC showdown.

Saints vs. Packers Odds, Spread and Total

Odds via DraftKings Sportsbook.

Spread

Saints +13.5 (-110)
Packers -13.5 (-110)

Moneyline

Saints: +550
Packers: -800

Total

42 (Over -108/Under -112)

Saints vs. Packers How to Watch

Date: Monday, Dec. 23
Time: 8:15 p.m. EST
Venue: Lambeau Field
How to Watch (TV): ABC/ESPN
Saints record: 5-9
Packers record: 10-4

Saints vs. Packers Betting Trends

The Packers are 8-6 against the spread this season.
The Saints are 6-8 against the spread this season.
The Saints are 0-4 straight up without Derek Carr this season.
The Packers are 3-2 ATS as home favorites in 2024.
The Saints are 2-2 ATS as road dogs in 2024.
The OVER is 7-7 in the Saints’ game this season.
The UNDER is 7-6-1 in the Packers' games this season.

Saints vs. Packers Injury Reports

Saints Injury Report

Tanoh Kpassagnon – questionable
Alvin Kamara – questionable
Derek Carr – questionable
Kool-Aid McKinstry – questionable

Packers Injury Report

Javon Bullard – questionable
Jaire Alexander – questionable
Quay Walker – questionable

Saints vs. Packers Key Players to Watch

New Orleans Saints

Alvin Kamara: With Carr’s status up in the air, Kamara is going to be leaned on heavily – if he can play – in Week 16. Kamara suffered a groin injury in Week 15, but he’s played through ailments all season long, including a broken hand. Last week, Kamara had 70 total yards and a score on nine touches despite playing just 45 percent of the team’s snaps.

Green Bay Packers

Romeo Doubs: After missing a few games with a concussion, Romeo Doubs returned to action and promptly made an impact on Sunday night against Seattle. The Packers receiver caught three of his five targets for 40 yards and two touchdowns, pushing him to 523 receiving yards and four scores in the 2024 season.

Saints vs. Packers Prediction and Pick

If Carr ends up getting ruled out for this game, I cannot back the Saints against a Green Bay team that should make some noise in the playoffs this season.

The Saints have losses by 24, 23, 18 and one point in the games that Carr missed, and they fell behind big on Sunday against Washington before Rattler orchestrated a second-half comeback.

Rattler is the better option to Haener under center, but the rookie has had his own struggles in games this season.

Meanwhile, the Packers have won three of their last four (the only loss came to Detroit), taking those games by 17, 28 and 13 points. Jordan Love is really thriving at this point in the season, throwing for seven scores and zero interceptions in his last four games.

I expect Green Bay to run away with this game against a Saints team that should be more focused on the upcoming 2024 NFL Draft.

Pick: Packers -13.5 (-110)