Deion Sanders Health Press Conference Live Updates: Latest On Colorado Buffaloes Coach

This offseason has been a little different for Deion Sanders as the Colorado Buffaloes' third-year head coach has spent the summer at his home in Texas recovering from an undisclosed health issue.

After remaining hush about the nature of his health problem at Big 12 football media days earlier this month, "Coach Prime" is expected to address his latest ailment during a press conference on Monday. Sanders will be joined by his medical team, including representatives from the University of Colorado's Anschutz Medical Campus, to reveal what has plagued him this summer.

About all that's publicly known regarding Sanders' health issue is that he lost 14 pounds. "What I’m dealing with right now is at a whole 'nother level," Sanders said on former NFL cornerback Asante Samuel's podcast in late May.

Deion Sanders Health Press Conference Live Updates Latest Colorado Buffaloes Training Camp News Coach Prime Sick Return — Apr 19, 2025; Boulder, CO, USA; Colorado Buffaloes head coach Deion Sanders during the spring game at Folsom Field. Mandatory Credit: Isaiah J. Downing-Imagn Images | Isaiah J. Downing-Imagn Images

During Big 12 media days, "Coach Prime" was questioned about his health, but was quick to redirect the focus to his team. The Buffs won nine games last season and are now aiming to win the Big 12 Conference in Sanders' third year at the helm.

"I'm doing wonderful," Sanders said at Big 12 media days. "Don't I look good?... I'm not here to talk about my health. I'm here to talk about my team."

While recovering at his home in Texas, Sanders was visited by former Dallas Cowboys teammate Michael Irvin, rapper Lil Wayne, former Colorado superstar Travis Hunter and others. Irvin, a fellow Pro Football Hall of Famer, was optimistic that Sanders would recover. "I guarantee you he's going to be ok," Irvin said on his podcast after the visit.

"Coach Prime" has battled a series of health issues in recent years, including having two toes amputated in 2021. Two years later, he underwent multiple surgeries to remove blood clots in his leg.

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Sanders made a public appearance last week when he visited the Tampa Bay Buccaneers' training camp to watch his second-oldest son, safety Shilo Sanders, who recently signed an undrafted free agent contract with the Bucs. Deion Sanders' youngest son, quarterback Shedeur Sanders, is also navigating his first NFL training camp with the Cleveland Browns.

Colorado opened its preseason training camp on Monday ahead of its 2025 campaign. "Coach Prime" and the Buffs will host the ACC's Georgia Tech Yellow Jackets in their season opener on Aug. 29.

This article will be updated throughout Sanders' Monday press conference:

Randy Moss Called "Coach Prime" Every Other Day

All-time great NFL wide receiver Randy Moss, who's dealing with his own battle with cancer, called "Coach Prime" every other day to offer support. "Coach Prime" also thanked former Colorado star Travis Hunter, CU athletic director Rick George, Michael Irvin, rapper Lil Wayne and others in his support system.

Stepping Down From The Colorado Buffaloes Was Never An Option

Stepping down from his head coaching job at Colorado was never on Deion Sanders' mind.

"I always knew I was gonna coach again," Sanders said. "It was never in my spirit, in my heart, that God wouldn't allow me to coach again."

"Coach Prime" Opens Up On Having To Write A Will

On Sunday, Deion Sanders Jr. posted an emotional video of "Coach Prime" speaking on the struggles of having to write a will in May.

#CUBuffs HC Deion Sanders on having to write a will: "You don't want to be a fool and leave without having your business and affairs in order. Funny thing is, you up there ranking your kids again."
— Oliver Hayes (@ocuhayes) July 28, 2025

"Trying To Be The Best Prime For Everybody"

"I'm always looking up," Sanders said. "I'm always trying to go get it. I'm trying to be the best Prime for everybody."

Deion Sanders Says He Lost 25 Pounds

Deion Sanders said he lost 25 pounds while dealing with bladder cancer. He's now down about 12 pounds but is still managing issues with his bladder and using the bathroom.

Coach Prime on his battle with a bladder tumor: “The process wasn’t easy … everybody, get checked out.

“Without wonderful people like this, I probably wouldn’t be sitting here today.”

Added he lost 25 pounds and is still dealing with problems using the bathroom.
— Scott Procter (@ScottProcter_) July 28, 2025

Deion Sanders Diagnosed With Bladder Cancer, Now Cured

"Coach Prime" and his medical team revealed that he was diagnosed with bladder cancer in April. He had his bladder removed and is now cancer-free.

Deion Sanders Excited To Begin Fall Camp

Colorado held its first team meeting on Sunday and "Coach Prime" informed the team of his health issues.

"It was so wonderful seeing the team yesterday," Sanders said.

Coach Prime Joined By CU Athletic Trainer Lauren Askevold, UC Health Director of Urological Oncology Janet Kukreja

Here for Coach Prime’s first press conference of fall camp. Stay tuned for live updates at the link below. pic.twitter.com/gke3Dk4xOV
— Jack Carlough (@Jack_Carlough) July 28, 2025