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Fans cheer as Louisville Cardinals tight end Jaleel Skinner (88) scored a touchdown and greeted them during the Louisville-Villanova game Friday Sept. 11, 2026 at L&N Stadium in Louisville, Ky.

Ole Miss (1-0) vs Charlotte (0-1) (Ole Miss -45.5) 7:45 pm ESPN2 The Cards fell just short of upsetting the #9 Rebels last week. We learned that the offense fo

Fans cheer as Louisville Cardinals tight end Jaleel Skinner (88) scored a touchdown and greeted them during the Louisville-Villanova game Friday Sept. 11, 2026 at L&N Stadium in Louisville, Ky.

Ole Miss (1-0) vs Charlotte (0-1) (Ole Miss -45.5) 7:45 pm ESPN2 The Cards fell just short of upsetting the #9 Rebels last week. We learned that the offense fo

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Sep 5, 2025; Louisville, Kentucky, USA; The Louisville Cardinals mascot leads the team to greet fans during the Card March before facing off against the James Madison Dukes at L&N Federal Credit Union Stadium. Mandatory Credit: Jamie Rhodes-Imagn Images

Week Zero and the opening weeknight slate of college football has come and gone & we have seen many of Louisville’s future opponents already in action. Going f

Louisville Defense vs Clemson in 2025.

We made it! It’s been 222 days since the losingest program in college football history; the Indiana Hoosiers & their Heisman trophy winner Fernando Mendoza lif

Sep 27, 2025; Pittsburgh, Pennsylvania, USA; Louisville Cardinals head coach Jeff Brohm (right) leads the team onto the field to play the Pittsburgh Panthers at Acrisure Stadium. Mandatory Credit: Charles LeClaire-Imagn Images

Football

The Cardinals are generating a lot of hype ahead of year four under Jeff Brohm.

Dec 23, 2025; Boca Raton, FL, USA; Louisville Cardinals running back Isaac Brown (1) rushes for a first down during the fourth quarter of the Boca Raton Bowl at Flagler CU Stadium. Mandatory Credit: Jeff Romance-Imagn Images

Football

A pair of Cardinals are already generating very early buzz for the Heisman Trophy.

Nov 29, 2025; Louisville, Kentucky, USA; Louisville Cardinals tight end Jacob Stewart (86) celebrates with tight end Nate Kurisky (85) after scoring a touchdown against the Kentucky Wildcats during the first half at L&N Federal Credit Union Stadium. Mandatory Credit: Jamie Rhodes-Imagn Images

Football

The Cardinals head down to South Florida to take on the Rockets in their final game of the 2025 season.

Nov 22, 2025; Dallas, Texas, USA; Louisville Cardinals quarterback Deuce Adams (13) throws the ball during the second half against the SMU Mustangs at Gerald J. Ford Stadium. Mandatory Credit: Jerome Miron-Imagn Images

Football

The Cardinals return home to host the Wildcats for their annual Governor's Cup rivalry showdown.

Oct 5, 2024; Louisville, Kentucky, USA; Southern Methodist Mustangs running back Brashard Smith (1) runs the ball against Louisville Cardinals defensive back Tamarion McDonald (12) during the second half at L&N Federal Credit Union Stadium. Mandatory Credit: Jamie Rhodes-Imagn Images

Football

The Cardinals head to Dallas to take on the Mustangs in their final ACC game of the season.

Oct 19, 2024; Louisville, Kentucky, USA; Louisville Cardinals running back Isaac Brown (25) runs the ball against Miami Hurricanes defensive back D'Yoni Hill (19) during the first half at L&N Federal Credit Union Stadium. Mandatory Credit: Jamie Rhodes-Imagn Images

Football

The Cardinals hit the road on the other side of their final bye week to face Miami.

Mar 14, 2025; Charlotte, NC, USA; Louisville Cardinals guard J'Vonne Hadley (1) goes to the basket against the Clemson Tigers during the second half at Spectrum Center. Mandatory Credit: Jim Dedmon-Imagn Images

Basketball

The major sports books like the Cardinals' chances to win the conference this upcoming 2025-26 season.

Louisville Cardinals running back Duke Watson (26) celebrates his play during their game against the Austin Peay Governors on Saturday, Aug. 31, 2024 at L&N Federal Credit Union Stadium in Louisville, Ky.

Football

The Cardinals open up the 2025 season against the Colonels this Saturday.

Betting Odds Released for Louisville Head Coaching Vacancy

Basketball

Three coaches with Louisville ties headline the betting favorites to take over the Cardinals.