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Milwaukee Brewers pitcher Freddy Peralta is a good bet to go over his strikeouts prop on Monday night.

Brewers vs. Padres Prediction, Odds, Probable Pitchers and Prop Bets for Monday, Sept. 22

Ryan Gilbert

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Sep 22, 2025

Aug 12, 2025; San Francisco, California, USA; San Diego Padres shortstop Xander Bogaerts (2) smiles during warmups before the game against the San Francisco Giants at Oracle Park. Mandatory Credit: Robert Edwards-Imagn Images

Padres Notes: Xander Bogaerts’ Return Revealed, Friars All-Star Honors Clayton Kershaw, Magic Number Update

Aaron Coloma

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Sep 22, 2025

Washington Nationals starting pitcher MacKenzie Gore is a great prop target on Monday.

Walk-Off Wagers: MLB Best Bets Today (Predictions for Brewers vs. Padres, MacKenzie Gore)

Peter Dewey

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Sep 22, 2025

Sep 19, 2025; Chicago, Illinois, USA; San Diego Padres starting pitcher Dylan Cease (84) delivers a pitch against the Chicago White Sox during the first inning at Rate Field. Mandatory Credit: Kamil Krzaczynski-Imagn Images

Padres' Mike Shildt Still Believes in Dylan Cease as Postseason Nears

Aaron Coloma

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Sep 21, 2025

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Jul 22, 2025; Arlington, Texas, USA; Athletics glove and hat on the field before the game against the Texas Rangers at Globe Life Field. Mandatory Credit: Kevin Jairaj-Imagn Images

Former San Diego Padres Prospect Proving to be a "Dude" for A's

Jason Burke

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Sep 21, 2025

Sep 20, 2025; Chicago, Illinois, USA; San Diego Padres outfielder Jackson Merrill (3) high fives third baseman Manny Machado (13) , left, after his home run during the second inning against the Chicago White Sox at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

Padres' Magic Number Shrinks Following Series Win over White Sox

Aaron Coloma

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Sep 21, 2025

Sep 19, 2025; Los Angeles, California, USA; Los Angeles Dodgers pitcher Clayton Kershaw (22) salutes the crowd after being relieved during the fifth inning against the San Francisco Giants at Dodger Stadium. Mandatory Credit: Kiyoshi Mio-Imagn Images

Padres All-Star Sought Out Clayton Kershaw Autographed Jersey During Dodgers Series

Patrick Warren

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Sep 21, 2025

Aug 23, 2025; San Diego, California, USA; San Diego Padres shortstop Xander Bogaerts (2) celebrates after hitting an RBI double during the eighth inning against the Los Angeles Dodgers at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

Padres' Xander Bogaerts' Expected Return Date Revealed as Postseason Nears

Aaron Coloma

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Sep 21, 2025

Sep 20, 2025; Chicago, Illinois, USA; San Diego Padres first base Luis Arraez (4) grabs his helmet after popping up during the sixth inning against the Chicago White Sox at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

Padres Notes: Friars Offered Blockbuster Trade to Nationals at Deadline, All-Stars Talk Struggles, More

Aaron Coloma

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Sep 21, 2025

Sep 20, 2025; Chicago, Illinois, USA; San Diego Padres outfielders Jackson Merrill (3), Jackson Merrill (3) and and Gavin Sheets (30) point towards first baseman Ryan O'Hearn (32) after scoring on his three run double against the Chicago White Sox during the sixth inning at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

Padres’ Magic Number Shrinks After Much-Needed Win Over White Sox

Nelson Espinal

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Sep 21, 2025

Sep 13, 2025; San Diego, California, USA; San Diego Padres second baseman Luis Arraez (4) throws to first base for an out during the seventh inning against the Colorado Rockies at Petco Park. Mandatory Credit: David Frerker-Imagn Images

Padres All-Star on Team's Struggles: 'I Can't Wait for the Playoffs'

Patrick Warren

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Sep 20, 2025

Sep 9, 2025; San Diego, California, USA; San Diego Padres relief pitcher Mason Miller (22) celebrates after striking out a batter during the eighth inning against the Cincinnati Reds at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

Padres Don't Have a Josh Hader Like Problem With Mason Miller

Aaron Coloma

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Sep 20, 2025

Jul 10, 2022; San Diego, California, USA; San Diego Padres starting pitcher MacKenzie Gore (1) throws a pitch against the San Francisco Giants during the first inning at Petco Park. Mandatory Credit: Orlando Ramirez-Imagn Images

Padres Made 'Best Offer' for Mackenzie Gore at Trade Deadline: Report

Aaron Coloma

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Sep 20, 2025

San Diego Padres center fielder Jackson Merrill (3) is congratulated by Ryan O'Hearn (32) after hitting a solo home run during the fourth inning against the Colorado Rockies at Petco Park on Sept. 11.

Padres' All-Star Addition Gets Brutally Honest on Struggles

J.P. Hoornstra

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Sep 20, 2025

Sep 6, 2025; Denver, Colorado, USA; San Diego Padres manager Mike Shildt (8) looks on from the bench before the game against the Colorado Rockies at Coors Field. Mandatory Credit: Christopher Hanewinckel-Imagn Images

Padres Notes: Pitcher Not Happy With Mike Shildt, All-Star Linked to Dodgers, Major Playoff Prediction

Nelson Espinal

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Sep 20, 2025

Sep 13, 2025; San Diego, California, USA; San Diego Padres starting pitcher Dylan Cease (84) reacts after walking a batter during the fourth inning against the Colorado Rockies at Petco Park. Mandatory Credit: David Frerker-Imagn Images

Dodgers’ Magic Number Shrinks as Padres Suffer Brutal Loss to White Sox

Nelson Espinal

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Sep 19, 2025

Sep 17, 2025; New York City, New York, USA; San Diego Padres left fielder Ramon Laureano (5) celebrates with center fielder Jackson Merrill (3) and right fielder Fernando Tatis Jr. (23) after defeating the New York Mets at Citi Field. Mandatory Credit: Vincent Carchietta-Imagn Images

Padres Predicted to Upset NL Powerhouse in Wild Card Round

Aaron Coloma

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Sep 19, 2025

Jun 28, 2025; Cincinnati, Ohio, USA; San Diego Padres third baseman Manny Machado (13) reacts with first baseman Jake Cronenworth (9) after the victory over the Cincinnati Reds at Great American Ball Park. Mandatory Credit: Katie Stratman-Imagn Images

Padres Could Have Taken Over NL West From Dodgers, Says Manny Machado

Aaron Coloma

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Sep 19, 2025

Jul 5, 2025; Cumberland, Georgia, USA; Baltimore Orioles relief pitcher Scott Blewett (67) pitches against the Atlanta Braves during the sixth inning at Truist Park. Mandatory Credit: Dale Zanine-Imagn Images

Baltimore Orioles designate veteran reliever for assignment

John Sparaco

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Sep 19, 2025

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