College Football Week 1 Odds for Every Top 25 Game (Ohio State Favored against Texas)

The first week of the 2025 college football season is officially in the books, so sportsbooks across the country have posted the odds for the jam-packed Week 1.

There are plenty of great matchups in Week 1, but none are bigger than No. 1 Texas against No. 3 Ohio State, a rematch of last year's Cotton Bowl. Ohio State is set as a slight favorite in the rematch, but the game promises fireworks.

Let's take a look at the odds for all games involving top 25 ranked teams.

College Football Week 1 Odds for Top 25 Teams

All odds listed are via FanDuel Sportsbook

No. 25 Boise State vs. South Florida Odds, Spread, and Total

Spread

Boise State -6.5 (-105)
South Florida +6.5 (-115)

Moneyline

Boise State -210
South Florida +172

Total

OVER 63.5 (-110)
UNDER 63.5 (-110)

Western Illinois vs. No. 12 Illinois Odds, Spread, and Total

Spread

Western Illinois +45.5 (-115)
Illinois -45.5 (-105)

Moneyline

Total

OVER 63.5 (-110)
UNDER 63.5 (-110)

No. 1 Texas vs. No. 3 Ohio State Odds, Spread, and Total

Spread

Texas +2.5 (-110)
Ohio State -2.5 (-110)

Moneyline

Texas +106
Ohio State -128

Total

OVER 47.5 (-114)
UNDER 47.5 (-106)

Syracuse vs. No. 24 Tennessee Odds, Spread, and Total

Spread

Syracuse +13.5 (-105)
Tennessee -13.5 (-115)

Moneyline

Syracuse +440
Tennessee -610

Total

OVER 50.5 (-110)
UNDER 50.5 (-110)

Old Dominion vs. No. 20 Indiana Odds, Spread, and Total

Spread

Old Dominion +22.5 (-110)
Indiana -22.5 (-110)

Moneyline

Old Dominion +1100
Indiana -2500

Total

OVER 54.5 (-110)
UNDER54.5 (-110)

Nevada vs. No. 2 Penn State Odds, Spread, and Total

Spread

Nevada +44.5 (-105)
Penn State -44.5 (-115)

Moneyline

Total

OVER 57.5 (-105)
UNDER 57.5 (-115)

Marshall vs. No. 5 Georgia Odds, Spread, and Total

Spread

Marshall +39.5 (-110)
Georgia -39.5 (-110)

Moneyline

Total

OVER 55.5 (-102)
UNDER 55.5 (-120)

No. 8 Alabama vs. Florida State Odds, Spread, and Total

Spread

Alabama -13.5 (-110)
Florida State +13.5 (-110)

Moneyline

Alabama -550
Florida State +400

Total

OVER 50.5 (-110)
UNDER 50.5 (-110)

South Dakota vs. No. 22 Iowa State Odds, Spread, and Total

Spread

Moneyline

Total

Montana State vs. No. 7 Oregon Odds, Spread, and Total

Spread

Montana State +27.5 (-110)
Oregon -27.5 (-110)

Moneyline

Montana State +1600
Oregon -4500

Total

OVER 56.5 (-110)
UNDER 56.5 (-110)

Illinois State vs. No. 18 Oklahoma Odds, Spread, and Total

Spread

Illinois State +35.5 (-110)
Oklahoma -35.5 (-110)

Moneyline

Total

OVER 60.5 (-110)
UNDER 60.5 (-110)

Long Island University vs. No. 15 Florida Odds, Spread, and Total

Spread

Moneyline

Total

North Dakota vs. No. 17 Kansas State Odds, Spread, and Total

Spread

Moneyline

Total

UTSA vs. No. 19 Texas A&M Odds, Spread, and Total

Spread

UTSA +22.5 (-110)
Texas A&M -22.5 (-110)

Moneyline

UTSA +1000
Texas A&M -2100

Total

OVER 57.5 (-105)
UNDER 57.5 (-115)

No. 9 LSU vs. No. 4 Clemson Odds, Spread, and Total

Spread

LSU +3.5 (-105)
Clemson -3.5 (-115)

Moneyline

LSU +150
Clemson -182

Total

OVER 57.5 (-105)
UNDER 57.5 (-115)

New Mexico vs. No. 14 Michigan Odds, Spread, and Total

Spread

New Mexico +36.5 (-110)
Michigan -36.5 (-110)

Moneyline

Total

OVER 50.5 (-105)
UNDER 50.5 (-115)

Arkansas-Pine Bluff vs. No. 23 Texas Tech Odds, Spread, and Total

Spread

Moneyline

Total

Georgia State vs. No. 21 Ole Miss Odds, Spread, and Total

Spread

Georgia State +38.5 (-115)
Ole Miss -38.5 (-105)

Moneyline

Total

OVER 61.5 (-105)
UNDER 61.5 (-115)

East Texas A&M vs. No. 16 SMU Odds, Spread, and Total

Spread

Moneyline

Total

Northern Arizona vs. No. 11 Arizona State Odds, Spread, and Total

Spread

Northern Arizona +28.5 (-105)
Arizona State -28.5 (-115)

Moneyline

Northern Arizona +3000
Arizona State -10000

Total

OVER 52.5 (-110)
UNDER 52.5 (-110)

Virginia Tech vs. No. 13 South Carolina Odds, Spread, and Total

Spread

Virginia Tech +7.5 (-105)
South Carolina -7.5 (-115)

Moneyline

Virginia Tech +240
South Carolina -300

Total

OVER 49.5 (-110)
UNDER 49.5 (-110)

No. 6 Notre Dame vs. No. 10 Miami Odds, Spread, and Total

Spread

Notre Dame -2.5 (-110)
Miami +2.5 (-110)

Moneyline

Notre Dame -132
Miami +110

Total

OVER 50.5 (-115)
UNDER 50.5 (-105)

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Odds refresh periodically and are subject to change.

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