College Football Week 1 Odds for Every Top 25 Game (Ohio State Favored against Texas)

Iain MacMillan | Aug 25, 2025

Texas and Ohio State are set to face each other in Week 1 of college football action. / Tim Heitman-Imagn Images

The first week of the 2025 college football season is officially in the books, so sportsbooks across the country have posted the odds for the jam-packed Week 1.

There are plenty of great matchups in Week 1, but none are bigger than No. 1 Texas against No. 3 Ohio State, a rematch of last year's Cotton Bowl. Ohio State is set as a slight favorite in the rematch, but the game promises fireworks.

Let's take a look at the odds for all games involving top 25 ranked teams.

College Football Week 1 Odds for Top 25 Teams

All odds listed are via FanDuel Sportsbook

No. 25 Boise State vs. South Florida Odds, Spread, and Total

Spread

• Boise State -6.5 (-105)
• South Florida +6.5 (-115)

Moneyline

• Boise State -210
• South Florida +172

Total

• OVER 63.5 (-110)
• UNDER 63.5 (-110)

Western Illinois vs. No. 12 Illinois Odds, Spread, and Total

Spread

• Western Illinois +45.5 (-115)
• Illinois -45.5 (-105)

Moneyline

• N/A
• N/A

Total

• OVER 63.5 (-110)
• UNDER 63.5 (-110)

No. 1 Texas vs. No. 3 Ohio State Odds, Spread, and Total

Spread

• Texas +2.5 (-110)
• Ohio State -2.5 (-110)

Moneyline

• Texas +106
• Ohio State -128

Total

• OVER 47.5 (-114)
• UNDER 47.5 (-106)

Syracuse vs. No. 24 Tennessee Odds, Spread, and Total

Spread

• Syracuse +13.5 (-105)
• Tennessee -13.5 (-115)

Moneyline

• Syracuse +440
• Tennessee -610

Total

• OVER 50.5 (-110)
• UNDER 50.5 (-110)

Old Dominion vs. No. 20 Indiana Odds, Spread, and Total

Spread

• Old Dominion +22.5 (-110)
• Indiana -22.5 (-110)

Moneyline

• Old Dominion +1100
• Indiana -2500

Total

• OVER 54.5 (-110)
• UNDER54.5 (-110)

Nevada vs. No. 2 Penn State Odds, Spread, and Total

Spread

• Nevada +44.5 (-105)
• Penn State -44.5 (-115)

Moneyline

• N/A
• N/A

Total

• OVER 57.5 (-105)
• UNDER 57.5 (-115)

Marshall vs. No. 5 Georgia Odds, Spread, and Total

Spread

• Marshall +39.5 (-110)
• Georgia -39.5 (-110)

Moneyline

• N/A
• N/A

Total

• OVER 55.5 (-102)
• UNDER 55.5 (-120)

No. 8 Alabama vs. Florida State Odds, Spread, and Total

Spread

• Alabama -13.5 (-110)
• Florida State +13.5 (-110)

Moneyline

• Alabama -550
• Florida State +400

Total

• OVER 50.5 (-110)
• UNDER 50.5 (-110)

South Dakota vs. No. 22 Iowa State Odds, Spread, and Total

Spread

• N/A
• N/A

Moneyline

• N/A
• N/A

Total

• N/A
• N/A

Montana State vs. No. 7 Oregon Odds, Spread, and Total

Spread

• Montana State +27.5 (-110)
• Oregon -27.5 (-110)

Moneyline

• Montana State +1600
• Oregon -4500

Total

• OVER 56.5 (-110)
• UNDER 56.5 (-110)

Illinois State vs. No. 18 Oklahoma Odds, Spread, and Total

Spread

• Illinois State +35.5 (-110)
• Oklahoma -35.5 (-110)

Moneyline

• N/A
• N/A

Total

• OVER 60.5 (-110)
• UNDER 60.5 (-110)

Long Island University vs. No. 15 Florida Odds, Spread, and Total

Spread

• N/A
• N/A

Moneyline

• N/A
• N/A

Total

• N/A
• N/A

North Dakota vs. No. 17 Kansas State Odds, Spread, and Total

Spread

• N/A
• N/A

Moneyline

• N/A
• N/A

Total

• N/A
• N/A

UTSA vs. No. 19 Texas A&M Odds, Spread, and Total

Spread

• UTSA +22.5 (-110)
• Texas A&M -22.5 (-110)

Moneyline

• UTSA +1000
• Texas A&M -2100

Total

• OVER 57.5 (-105)
• UNDER 57.5 (-115)

No. 9 LSU vs. No. 4 Clemson Odds, Spread, and Total

Spread

• LSU +3.5 (-105)
• Clemson -3.5 (-115)

Moneyline

• LSU +150
• Clemson -182

Total

• OVER 57.5 (-105)
• UNDER 57.5 (-115)

New Mexico vs. No. 14 Michigan Odds, Spread, and Total

Spread

• New Mexico +36.5 (-110)
• Michigan -36.5 (-110)

Moneyline

• N/A
• N/A

Total

• OVER 50.5 (-105)
• UNDER 50.5 (-115)

Arkansas-Pine Bluff vs. No. 23 Texas Tech Odds, Spread, and Total

Spread

• N/A
• N/A

Moneyline

• N/A
• N/A

Total

• N/A
• N/A

Georgia State vs. No. 21 Ole Miss Odds, Spread, and Total

Spread

• Georgia State +38.5 (-115)
• Ole Miss -38.5 (-105)

Moneyline

• N/A
• N/A

Total

• OVER 61.5 (-105)
• UNDER 61.5 (-115)

East Texas A&M vs. No. 16 SMU Odds, Spread, and Total

Spread

• N/A
• N/A

Moneyline

• N/A
• N/A

Total

• N/A
• N/A

Northern Arizona vs. No. 11 Arizona State Odds, Spread, and Total

Spread

• Northern Arizona +28.5 (-105)
• Arizona State -28.5 (-115)

Moneyline

• Northern Arizona +3000
• Arizona State -10000

Total

• OVER 52.5 (-110)
• UNDER 52.5 (-110)

Virginia Tech vs. No. 13 South Carolina Odds, Spread, and Total

Spread

• Virginia Tech +7.5 (-105)
• South Carolina -7.5 (-115)

Moneyline

• Virginia Tech +240
• South Carolina -300

Total

• OVER 49.5 (-110)
• UNDER 49.5 (-110)

No. 6 Notre Dame vs. No. 10 Miami Odds, Spread, and Total

Spread

• Notre Dame -2.5 (-110)
• Miami +2.5 (-110)

Moneyline

• Notre Dame -132
• Miami +110

Total

• OVER 50.5 (-115)
• UNDER 50.5 (-105)

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