Two 4-4 teams heading in opposite directions will square off at the Superdome on Sunday when the New Orleans Saints host the San Francisco 49ers. The Saints have won their last two games to claim sole possession of first place in the NFC South, while the 49ers have dropped two in a row to fall three games behind the NFC West-leading Arizona Cardinals, who boast the conference’s best record at 7-1. New Orleans is a consensus five-point home favorite and has also beaten the spread in three straight.
The Saints are coming off an impressive 28-10 win against the Carolina Panthers as three-point road favorites at sportsbooks monitored by OddsShark.com on Thursday Night Football. They played very well defensively in limiting the Panthers to their second-lowest point total this season, as the UNDER cashed for the first time in their last five games and just the second time this year. New Orleans is 6-1-1 ATS in its past eight home games against NFC West opponents but 0-3-1 vs. the line in the last four meetings with San Francisco overall.
Meanwhile, the 49ers returned from a bye week hoping to get back on the winning track after getting routed 42-17 by the Denver Broncos on the road as 6.5-point underdogs. Instead, they struggled offensively in a 13-10 loss to the St. Louis Rams, with the closing NFL betting lines showing them as 10.5-point home favorites. San Francisco quarterback Colin Kaepernick fumbled on the goal line while attempting the game-winning touchdown on a run up the middle with two seconds remaining against the Rams, and the team will now try to bounce back on the road, where they are 2-2 straight-up and against the spread this season.
There are three intriguing divisional matchups on Sunday afternoon in Week 10, at least from a betting perspective. The Atlanta Falcons (2-6) return from their bye week and visit the Tampa Bay Buccaneers (1-7) as 1.5-point road favorites in the NFC South. The Falcons have lost six of their last seven road games against divisional opponents, going 0-6-1 ATS. The Denver Broncos (6-2) visit the Oakland Raiders (0-8) as 11.5-point chalk, and they have gone 8-1 vs. the line in their past nine road games against AFC West foes. Arizona has covered six of its last seven games and will host St. Louis (3-5) in an NFC West matchup as a seven-point home favorite.