Miami has not put out an injury report, and Wake's availability for the game is uncertain.
Wake was injured in the first quarter of Sunday's 27-23 victory over the Atlanta Falcons. It was reported earlier in the week that he would likely miss two to three weeks with a knee injury.
Wake did not participate in team drills on Wednesday, and wore sweatpants over top of a knee brace.
"All great competitors want to play,'' coach Joe Philbin said to the Miami Herald. "We certainly would never put out a player we thought wasn't ready to play the game and protect himself, so we'll just see how practice goes.''
BURKE: First Down/Fourth Down: Ryan Tannehill gets the job done again for Dolphins Wake has never missed a game because of injury in his five NFL seasons. He leads the Dolphins with 2 1/2 sacks this season.