Barcelona says midfielders Cesc Fabregas and Alex Song, and defender Adriano, have all recovered from their respective injuries and are fit to play.
Fabregas hasn't played since pulling a muscle in his left leg during a game on Dec. 9, ruling him out for the past three matches.
Song and Adriano both missed one match with leg knocks.
Barcelona leads the Spanish league by nine points. It hosts crosstown rival Espanyol on Sunday as it aims to extend its league-record start of 16 wins and a draw.