Alabama vs. St. John’s Prediction, Odds and Best College Basketball Prop Bets for Saturday, Nov. 8

Iain MacMillan | Nov 8, 2025

St. John's is a home favorite against Alabama in Saturday's college basketball action. / Wendell Cruz-Imagn Images

St. John's 2025 NCAA Tournament run ended unceremoniously last season, losing to Arkansas in the Round of 32. They'll try to go on another run this season and repeat as Big East champions, and they enter the 2025-2026 campaign as the No. 5-ranked team in the country.

After disposing of Quinnipiac in their opening game, they'll now host No. 15 Alabama in this intriguing out-of-conference showdown. The Crimson Tide cruised past North Dakota in their season opener.

Let's dive into the odds and my best bet for this game.

Alabama vs. St. John's Odds, Spread, and Total

Odds via BetMGM Sportsbook

Spread

• Alabama +6.5 (-110)
• St. John's -6.5 (-110)

Moneyline

• Arkansas +225
• St. John's -275

Total

• OVER 168.5 (-110)
• UNDER 168.5 (-110)

Alabama vs. St. John's How to Watch

• Date: Saturday, Nov. 8
• Game Time: 12:00 pm ET
• Venue: Madison Square Garden
• How to Watch (TV): FS1
• Arkansas Record: 1-0
• St. John's Record: 1-0

Alabama vs. St. John's Key Player to Watch

• Dillon Mitchell, F - St. John's Red Storm

Dillon Mitchell is going to play a big role in St. John's success this season. The former Texas Longhorn and Cincinnati Bearcat has already made his presence known, putting up 18 points, seven rebounds, two assists, four steals, and one block in their season opener. We'll find out more as the season progresses, just how impactful a role he will play this season.

Alabama vs. St. John's Prediction and Pick

Alabama has struggled when facing elite defenses the past couple of seasons. Their ability to put up points in bunches from beyond the arc has worked against inferior opponents, but when they face a team that can shut down the perimeter, they have a tough time getting past them.

Unfortunately for them, St. John's has established itself as one of the best defensive teams in the country in the Rick Pitino era. St. John's has also re-tooled in the offseason and may be even better this year than they were last season.

I'll lay the points with the Red Storm at Madison Square Garden.

Pick: St. John's -6.5 (-110) via BetMGM

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