Is Ricky Pearsall Playing Today? (Injury Update, Betting Impact for Jaguars vs. 49ers)

The latest injury update for San Francisco 49ers wide receiver Ricky Pearsall in Week 4 against the Jacksonville Jaguars.

San Francisco 49ers wide receiver Ricky Pearsall. / Stephen Lew-Imagn Images

San Francisco 49ers wide receiver Ricky Pearsall is listed as questionable for Week 4 against the Jacksonville Jaguars due to a knee injury.

However, according to ESPN's Adam Schefter, Pearsall is expected to play in this matchup.

Both 49ers WRs listed as questionable for Sunday – Ricky Pearsall (knee), Jauan Jennings (shoulder, ankle) – are expected to play Sunday vs. the Jaguars, but Jennings also is likely to be limited, per sources. pic.twitter.com/ODks1irwPk

— Adam Schefter (@AdamSchefter) September 28, 2025

That's a major boost to the San Francisco offense, especially since starting quarterback Brock Purdy (toe) is set to return from a two-game absence in Week 4.

George Kittle and Brandon Aiyuk are both still out for the 49ers, so Pearsall could have a massive role in Week 4.

This season, the former first-round pick has 16 catches (on 24 targets) for 281 yards. He's averaging over 90 receiving yards per game, and he'll aim to keep that going -- despite his knee injury -- on Sunday.

If Pearsall is able to handle a normal workload, he could be a steal in the prop market in this matchup.

Best Ricky Pearsall Prop Bet for Week 4 vs. Jaguars

Odds via DraftKings Sportsbook

Ricky Pearsall OVER 59.5 Receiving Yards (-112)

In Week 1 with Purdy under center, Pearsall finished with four catches (on seven targets) for 108 yards. He’s coming off his best week of the season in Week 3, where he caught eight balls (on 11 targets) for 117 yards.

Even with Jauan Jennings (questionable) also expected to play in this game, I think Pearsall is the receiver to trust on Sunday.

Jennings is expected to be limited in Week 4, and the 49ers remain without Kittle and Aiyuk. Even in his worst game this season (Week 2), Pearsall finished with four catches for 56 yards.

With Purdy back, I think the former first-round pick could have a massive day as the No. 1 option in the passing game in Week 4.

---

Odds refresh periodically and are subject to change.

If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.

Claim the latest DraftKings promo code offer today. Sign up and place a $5 bet to earn a guaranteed $200 in bonus bets plus over $200 off NFL Sunday Ticket. Regardless of the outcome of your wager, DraftKings will add eight $25 bonus bet tokens to your new account and award one promo code for a discounted NFL Sunday ticket subscription.