Smith-Schuster was tackled from behind during the first half.
Steelers wide receiver JuJu Smith-Schuster suffered a left knee contusion during the first half of the Pro Bowl on Sunday. He was ruled questionable to return.
Midway through the second quarter, Smith-Schuster hauled in a pass from Colts quarterback Andrew Luck, then was brought down from behind by Seahawks linebacker Bobby Wagner. Following the play, Smith-Schuster limped off the field and did not re-enter the contest.
Trainers were shown tending to Smith-Schuster on the sideline.
Smith-Schuster is competing in his first Pro Bowl after being named a replacement for teammate Antonio Brown, who's injured.
Smith-Schuster, 23, became the youngest player in NFL history to record at least 100 receptions in a single season after recording 111 in 2018. The USC product also registered 1,426 receiving yards and seven touchdowns during his second professional season.