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San Francisco 49ers quarterback Brock Purdy (13).

Signs point to 49ers sitting Brock Purdy for the second week in a row

Grant Cohn
|
Sep 18, 2025

Why the 49ers have struggled to run the ball through two weeks

Parker Hurley
|
Sep 18, 2025
San Francisco 49ers head coach Kyle Shanahan.

Why these injuries could swing the 49ers' Week 2 matchup vs. Arizona

Parker Hurley
|
Sep 18, 2025
Sep 7, 2025; New Orleans, Louisiana, USA;  New Orleans Saints quarterback Spencer Rattler (2) scrambles out the pocket against the Arizona Cardinals during the second half at Caesars Superdome. Mandatory Credit: Stephen Lew-Imagn Images

49ers Coach Thinks Saints Have Star In Spencer Rattler

Patrick McAvoy
|
Sep 18, 2025
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Sep 14, 2025; New Orleans, Louisiana, USA;  New Orleans Saints wide receiver Rashid Shaheed (22) is tackled by San Francisco 49ers linebacker Dee Winters (53) during the second half at Caesars Superdome. Mandatory Credit: Stephen Lew-Imagn Images

One 49ers Starter is Helping Unlock the Defense’s Potential

Jose Sanchez
|
Sep 18, 2025

Sep 7, 2025; Seattle, Washington, USA; San Francisco 49ers linebacker Fred Warner (54) reacts after the game against the Seattle Seahawks during the fourth quarter at Lumen Field. Mandatory Credit: Joe Nicholson-Imagn Images

Fred Warner Could Break a 49ers Franchise Record in Week 3

Henry Cheal
|
Sep 18, 2025

Arizona Cardinals quarterback Kyler Murray (1) scrambles out of the backfield against the Carolina Panthers at State Farm Stadium on Sept 14, 2025.

One Area the 49ers Will Find Challenging Versus the Cardinals

Jose Sanchez
|
Sep 17, 2025

Sep 14, 2025; New Orleans, Louisiana, USA;  New Orleans Saints running back Alvin Kamara (41) runs against San Francisco 49ers defensive tackle Alfred Collins (95) during the first half at Caesars Superdome. Mandatory Credit: Stephen Lew-Imagn Images

One Area the 49ers Have a Clear Advantage Over the Cardinals

Jose Sanchez
|
Sep 17, 2025

Purdy threw for two touchdowns, two interceptions and 277 passing yards in San Francisco's opener vs. the Seahawks.

Brock Purdy Injury: Kyle Shanahan Shares Positive Update Ahead of Week 3

Brigid Kennedy
|
Sep 17, 2025
Sep 7, 2025; Seattle, Washington, USA; San Francisco 49ers quarterback Brock Purdy (13) reacts following a failed third down play against the Seattle Seahawks during the fourth quarter at Lumen Field. Mandatory Credit: Joe Nicholson-Imagn Images

49ers Supply Encouraging Injury Update on Brock Purdy

Jose Sanchez
|
Sep 17, 2025

San Francisco 49ers offensive linemen Ben Bartch (78), Dominick Puni (77), Trent Williams (71) and Colton McKivitz (68) during an OTA at Levi's Stadium. Mandatory Credit: D. Ross Cameron-Imagn Images

49ers place starting offensive lineman on injured reserve

Grant Cohn
|
Sep 17, 2025

The Sports Illustrated team breaks down their picks to win all 16 games in Week 3 of the 2025 NFL season.

NFL Straight-Up Moneyline Picks for Every Game in Week 3

SI Staff
|
Sep 17, 2025

Sep 7, 2025; Seattle, Washington, USA; San Francisco 49ers linebacker Fred Warner (54) returns to the locker room for halftime against the Seattle Seahawks at Lumen Field. Mandatory Credit: Joe Nicholson-Imagn Images

Why Fred Warner is raving about this player on the 49ers defense

Henry Cheal
|
Sep 17, 2025

Aug 9, 2025; Santa Clara, California, USA;  San Francisco 49ers offensive lineman Connor Colby (75) pass protects San Francisco 49ers quarterback Tanner Mordecai (4) against Denver Broncos defensive lineman Jordan Jackson (94) in the second quarter at Levi's Stadium. Mandatory Credit: David Gonzales-Imagn Images

How the 49ers’ Offense Improves With Rookie Connor Colby Starting

Jose Sanchez
|
Sep 17, 2025

San Francisco 49ers general manager John Lynch.

Early signs the 49ers draft class may already be a hit

Parker Hurley
|
Sep 17, 2025

Buffalo Bills quarterback Josh Allen (17) drops back to pass against the New York Jets on Sunday.

On SI Week 3 NFL Power Rankings: Top 5 Teams Unchanged

Bill Huber
|
Sep 16, 2025

San Francisco 49ers cornerback Upton Stout.

The Good and Not So Good from the 49ers' Rookies After Two Games

Grant Cohn
|
Sep 16, 2025

Sep 14, 2025; New Orleans, Louisiana, USA; San Francisco 49ers head coach Kyle Shanahan runs on the field before game against the New Orleans Saints at Caesars Superdome. Mandatory Credit: Matthew Hinton-Imagn Images

Kyle Shanahan Raves About How This 49ers Rookie Improved in Week 2

Jose Sanchez
|
Sep 16, 2025

Sep 14, 2025; Indianapolis, Indiana, USA; Indianapolis Colts running back Jonathan Taylor (28) rushes for a touchdown during a game against the Denver Broncos at Lucas Oil Stadium.

Week 2 Touches Report: Jonathan Taylor & Alvin Kamara Lead Week 2 Running Backs

Jason Sarney
|
Sep 16, 2025
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