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Sep 21, 2025; Santa Clara, California, USA; Arizona Cardinals running back Trey Benson (33) carries the ball as San Francisco 49ers safety Jason Pinnock (25) defends during the second half at Levi's Stadium. Mandatory Credit: Cary Edmondson-Imagn Images

Early Week 4 Waiver Wire Pickups: Trey Benson & Luther Burden III Emerge as League-Winning Pickups

Michael Rovetto
|
Sep 21, 2025
Puka Nacua got called for a huge penalty because the refs thought he was taunting the Eagles after a big catch.

NFL Week 3 Awards: Refs Hit Rams With Dumbest Penalty During Loss to Eagles

Andy Nesbitt
|
Sep 21, 2025
Sep 21, 2025; Santa Clara, California, USA; San Francisco 49ers fullback Kyle Juszczyk (44) celebrates after scoring a touchdown against the Arizona Cardinals during the second half at Levi's Stadium. Mandatory Credit: Kyle Terada-Imagn Images

5 Blunt Takeaways From the 49ers' Tough Win Against the Cardinals

Jose Sanchez
|
Sep 21, 2025
Sep 21, 2025; Santa Clara, California, USA; Arizona Cardinals head coach Jonathan Gannon on the sidelines against the San Francisco 49ers during the second half at Levi's Stadium. Mandatory Credit: Kyle Terada-Imagn Images

Cardinals Collapse as 49ers Nail Game-Winning Field Goal

Donnie Druin
|
Sep 21, 2025
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Marvin Harrison Jr. reacts after dropping a wide open pass during the Arizona Cardinals' Week 3 matchup with the San Francisco 49ers.

Marvin Harrison Jr. Drops Easiest Catch He'll See All Day vs. 49ers

Ryan Phillips
|
Sep 21, 2025

Arizona Cardinals quarterback Kyler Murray (1) warms up before their preseason game against the Kansas City Chiefs at State Farm Stadium on Aug. 9, 2025.

Cardinals’ Kyler Murray Joins Josh Allen in NFL History

Donnie Druin
|
Sep 21, 2025

Conner was carted off the field early in the third quarter.

James Conner Injury: Cardinals RB Carted Off Field vs. 49ers

Tom Dierberger
|
Sep 21, 2025

Sep 21, 2025; Santa Clara, California, USA; Arizona Cardinals running back James Conner (6) is tackled by San Francisco 49ers linebacker Dee Winters (53) during the first half at Levi's Stadium. Mandatory Credit: Cary Edmondson-Imagn Images

Cardinals RB James Conner Carted Off After Gruesome Injury

Donnie Druin
|
Sep 21, 2025

Jan 5, 2025; Glendale, Arizona, USA; San Francisco 49ers defensive end Nick Bosa (97) against the Arizona Cardinals at State Farm Stadium. Mandatory Credit: Mark J. Rebilas-Imagn Images

49ers Lose Star Defender vs Cardinals

Donnie Druin
|
Sep 21, 2025
Sep 14, 2025; New Orleans, Louisiana, USA;  San Francisco 49ers quarterback Mac Jones (10) passes against the New Orleans Saints during the first half at Caesars Superdome. Mandatory Credit: Stephen Lew-Imagn Images

Last-Minute Predictions for Cardinals vs 49ers

Richie Bradshaw
|
Sep 21, 2025

Aug 9, 2025; Glendale, Arizona, USA; Arizona Cardinals offensive tackle Paris Johnson Jr. (70) against the Kansas City Chiefs during a preseason NFL game at State Farm Stadium. Mandatory Credit: Mark J. Rebilas-Imagn Images

Cardinals Suffer Brutal Last-Second Blow vs 49ers

Donnie Druin
|
Sep 21, 2025

Sep 7, 2025; New Orleans, Louisiana, USA; Arizona Cardinals head coach Jonathan Gannon looks on against the New Orleans Saints at Caesars Superdome. Mandatory Credit: Stephen Lew-Imagn Images

Gameplan: How Cardinals Can Upset 49ers

Richie Bradshaw
|
Sep 21, 2025

Arizona Cardinals linebacker Josh Sweat (10) works out during the team's practice at State Farm Stadium on July 29, 2025.

3 Cardinals Who Can Flip the Script vs 49ers

Richie Bradshaw
|
Sep 21, 2025

Sep 14, 2025; New Orleans, Louisiana, USA; San Francisco 49ers tight end Luke Farrell (89) celebrates a touchdown with San Francisco 49ers quarterback Mac Jones (10) during the first quarter against the New Orleans Saints at Caesars Superdome. Mandatory Credit: Matthew Hinton-Imagn Images

Cardinals Must Contain These 49ers in Week 3

Richie Bradshaw
|
Sep 21, 2025

Dec 15, 2024; Glendale, Arizona, USA; Arizona Cardinals defensive end Darius Robinson (56) against the New England Patriots at State Farm Stadium. Mandatory Credit: Mark J. Rebilas-Imagn Images

5 Arizona Cardinals Who Must Step Up vs 49ers

Donnie Druin
|
Sep 21, 2025

Sep 14, 2025; Glendale, Arizona, USA;  Arizona Cardinals quarterback Kyler Murray (1) warms up prior to the first half against the Carolina Panthers at State Farm Stadium. Mandatory Credit: Matt Kartozian-Imagn Images

Madden 26 Predicts Cardinals at 49ers Week 3 Matchup

Donnie Druin
|
Sep 21, 2025

Sep 14, 2025; New Orleans, Louisiana, USA;  San Francisco 49ers wide receiver Jauan Jennings (15) reacts to scoring a touchdown against the New Orleans Saints during the second half at Caesars Superdome. Mandatory Credit: Stephen Lew-Imagn Images

49ers Reportedly Lose Top Weapon for Cardinals Matchup

Donnie Druin
|
Sep 21, 2025

Jul 24, 2025; Glendale, AZ, USA; Arizona Cardinals running back James Conner during training camp at State Farm Stadium. Mandatory Credit: Mark J. Rebilas-Imagn Images

Arizona Cardinals Fantasy Football Guide: Week 3 at San Francisco 49ers

Kelly Singh
|
Sep 21, 2025

Aug 9, 2025; Glendale, Arizona, USA; Arizona Cardinals wide receiver Marvin Harrison Jr. (18) against the Kansas City Chiefs during a preseason NFL game at State Farm Stadium. Mandatory Credit: Mark J. Rebilas-Imagn Images

Week 3 Staff Predictions: Arizona Cardinals at San Francisco 49ers

Donnie Druin
|
Sep 21, 2025
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