Liverpool have received a major boost ahead of Wednesday's second leg tie against Roma, with Diego Perotti and Kevin Strootman ruled out for the semi final clash.
Perotti made an instant impact off the bench in the first leg, scoring Roma's second goal of the night in I Giallorossi's 5-2 defeat at Anfield.
His goal provided a glimmer of hope for the Italians ahead of the return leg in Rome, however news of his injury will come as another blow to the Italian's chances.
Roma boss Eusebio Di Francesco confirmed the news to La Gazetta Dello Sport, saying that the Argentinian international will miss the second leg after picking up an ankle injury at Anfield.
Di Francesco also confirmed that Strootman in unlikely to recover from a knock in time for Wednesday's fixture against the Reds.
This news will do little to raise moral within Roma's ranks as they prepare for what they hope will be yet another unlikely second leg comeback. However, I Giallorossi will take encouragement from their 4-1 victory over Chievo on Saturday - such a result would see them progress to the final in Kiev.
Roma recorded the comfortable victory over Serie A strugglers Chievo and in spite of a Juan Jesus red card - the Brazilian still suffering from trauma caused by Salah - Di Francesco's men were able to score the required four goals that they will likely need on Wednesday.
Patrik Schick, Stephan El Shaarawy and Edin Dzeko were all on the score sheet in a victory that saw Roma gain a tighter hold on a Champions League spot ahead of next season.