The team said the guard sustained a ''hairline fracture of the great right toe'' in Monday night's game.
He's expected to miss at least two weeks. Surgery is not required.
Prigioni exited with 9:49 left in the third quarter and the Knicks trailing 57-42.
He was replaced by Beno Udrih.
Prigioni was starting in place of Raymond Felton, who remains sidelined with a strained left hamstring.
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