Right now across the web, thousands of fantasy pundits are telling you not to overreact to Week 1. In some cases, they're right. Maybe Cam Newton was criminally underrated heading into his rookie year, but he's not going to play the Cardinals every week. You shouldn't be trying to deal Chris Johnson for anything less than full value. And yes, Cadillac Williams is the must-add of the week.
However, there are also cases where what appears to be an overreaction to Week 1 is actually the proper reaction. Even though we've only seen 60 minutes of football from each of the following guys, I'm already trying to trade the ones I own, and would be trying to move the others if I had them in any of my leagues.