Brewers' Jacob Misiorowski Leaves MLB Debut With Ankle Injury in Middle of No Hitter

The Milwaukee starter was brilliant in his debut before rolling his ankle between pitches in the sixth inning.

Milwaukee Brewers starting pitcher Jacob Misiorowski was brilliant in his major league debut. / Jeff Hanisch-Imagn Images

Milwaukee Brewers rookie Jacob Misiorowski was brilliant in his major league debut on Thursday night against the St. Louis Cardinals, as the flamethrower went five innings without allowing a hit.

Misiorowski took the mound in the sixth to continue his no-hit bid, but after throwing three straight balls to Cardinals outfielder Victor Scott, Misiorowski rolled his ankle between pitches as he walked back to the mound.

This is the most Brewers thing ever: Jacob Misiorowski has a no-hitter through five innings of his Major League debut and destroys his ankle walking back to the pitcher's mound. pic.twitter.com/rx4Sm1sD7k

— Dan O'Donnell (@DanODonnellShow) June 13, 2025

Misiorowski left the game as a precaution, but not before going five-plus innings, allowing no hits while recording five strikeouts and four walks. He also threw 14 pitches of at least 100 miles per hour.

Jacob Misiorowski recorded 14 pitches at 100+ MPH and didn't allow a hit in his highly anticipated Major League debut 🔥 pic.twitter.com/sBMp44qETX

— MLB (@MLB) June 13, 2025

Misiorowski told reporters after the game that he was cramping up which caused him to roll his ankle, but that he's O.K. and isn't dealing with anything serious after his first start.

The Brewers went on to win 6–0.

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