NFL odds: Chargers, Cowboys look to continue strong record against spread

The San Diego Chargers and the Dallas Cowboys are both 5-1 and lead their respective divisions, and each is among the best teams in the league against the spread this season. Those teams have marquee divisional matchups taking place on Sunday afternoon, with Kansas City at San Diego and the Giants at Dallas.

San Diego is 5-1 ATS (matching its straight-up record) and is a four-point favorite against the Chiefs (2-3), while Dallas is 4-2 against the line and seven-point chalk facing the Giants (3-3) at sportsbooks monitored by OddsShark.com. The Chargers, however, have covered just three of their last 10 home games against AFC West opponents, and the Cowboys have dropped four of the past five home meetings with New York both SU and ATS.

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The other divisional game is far less exciting on paper considering how poorly the St. Louis Rams (1-4) just performed on Monday Night Football. The defending Super Bowl champion Seattle Seahawks (3-2) visit the Rams earlier Sunday fresh off a 30-23 home loss to the Dallas Cowboys last week as 9.5-point favorites. You can bet the Seahawks will be playing mad with the NFL odds for Week 7 showing them as 7.5-point chalk at St. Louis. The Rams blew an early 14-0 lead against the San Francisco 49ers on Monday and lost 31-17 as 3.5-point home underdogs. 

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Two other key games -- one in each conference -- take place earlier in the day as well. In the AFC, the Indianapolis Colts (4-2) will go for their fifth straight win as they host the Cincinnati Bengals (3-1-1) as three-point favorites. In the NFC, the New Orleans Saints (2-3) will try to beat the Detroit Lions (4-2) for the fifth time in a row as 2.5-point underdogs following their bye week. The Saints vs. Lions betting matchup is especially intriguing since New Orleans has lost six straight road games in the regular season.

Five more AFC versus NFC matchups on Sunday include the Tennessee Titans (2-4) visiting the Washington Redskins (1-5); the Baltimore Ravens (4-2) hosting the Atlanta Falcons (2-4); the Buffalo Bills (3-3) taking on the Minnesota Vikings (2-4); the Miami Dolphins (2-3) squaring off against the Chicago Bears (3-3); and the Oakland Raiders (0-5) meeting the Arizona Cardinals (4-1). The favored teams in those games are the Redskins (-5.5), Ravens (-7.5), Bills (-7), Bears (-3) and Cardinals (-3).