ARIZONA (1-3) at SAN FRANCISCO (1-3)
Thursday, 8:25 p.m. EDT, CBS/NFL Network
OPENING LINE - Cardinals by 5 1/2
RECORD VS. SPREAD - Arizona 1-3, San Francisco 1-3
SERIES RECORD - 49ers lead 29-20
LAST MEETING - Cardinals beat 49ers 19-13, Nov. 29, 2015
LAST WEEK - Cardinals lost to Rams 17-13; 49ers lost to Cowboys 24-17
AP PRO32 RANKING - Cardinals No. 20, 49ers No. 31
CARDINALS OFFENSE - OVERALL (7), RUSH (14), PASS (7).
CARDINALS DEFENSE - OVERALL (8), RUSH (20), PASS (7).
49ERS OFFENSE - OVERALL (28), RUSH (9), PASS (31).
49ERS DEFENSE - OVERALL (26), RUSH (32), PASS (14).
STREAKS, STATS AND NOTES - Cardinals snapped six-game road skid vs. Niners last year and swept season series for first time since 2008. ... Arizona QB Carson Palmer out with concussion. Backup Drew Stanton went 5-3 as starter in 2014. ... Cardinals RB David Johnson had 124 scrimmage yards last week and has topped 100 yards from scrimmage in four straight. ... Arizona WR Larry Fitzgerald has 19 catches for 200 yards, two TDs in last two meetings with San Francisco. ... Cardinals LB Chandler Jones has sacks in all four games this season. ... 49ers RB Carlos Hyde has five TDs rushing and team has seven this season. ... San Francisco QB Blaine Gabbert threw for 318 yards, one TD in last meeting vs. Cardinals. ... Niners will be without top defender LB NaVorro Bowman (ruptured Achilles tendon). ... San Francisco has allowed only three sacks all season. ... 49ers allowed 100-yard rusher in three straight games for first time in single season since 2004. ... Fantasy Tip: 49ers WR Jeremy Kerley has been targeted at least six times each game and leads team with 32 targets, leading to 18 catches for 202 yards and one TD.
AP NFL website: www.pro32.ap.org and www.twitter.com/AP-NFL