Auburn will join Texas Tech with its first Final Four appearance on April 6.
The Tigers overcame a five-point halftime deficit to win the Midwest regional. After losing a 58-54 lead in the final five minutes of regulation, Bruce Pearl's squad outscored the Wildcats 16-11 in overtime. John Calipari and Kentucky have not reached the Final Four since 2015.
Junior guard Jared Harper led Auburn with 26 points on Sunday. Senior Bryce Brown added 24 points on 8-12 from the field.
P.J. Washington carried Kentucky offensively on Sunday, tallying 28 points on 10-17 shooting. The sophomore forward added 13 rebounds in his first healthy appearance in the NCAA tournament. Washington sat out the first round as he nursed a foot injury.
Sunday marked Auburn's second Elite Eight appearance in school history. The Tigers will join Texas Tech as first-time participants in the Final Four.
Pearl reached his first Final Four on Sunday. He previously took Tennessee to the Elite Eight in 2010.