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#11 Oregon vs. #6 South Carolina Prediction, Picks & Odds Today, 3/21

One of the most intriguing matchups of the first round of the 2024 NCAA Tournament is between the #11 Oregon Ducks and #6 South Carolina Gamecocks, as they enter on polar opposite trajectories. Don’t worry - we’ll explain exactly what we mean as we break down our best Oregon vs. South Carolina prediction below.

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🏀 OREGON VS. SOUTH CAROLINA PREDICTION: Ducks Money Line (+100 at DraftKings)

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#11 Oregon vs. #6 South Carolina Prediction for Today's March Madness Game, 3/21

We stated this was arguably the most intriguing matchup of the Round of 64, and frankly, #6 vs. #11 matchups tend to be as it is. Picking a #11 seed in your bracket has been a rather advantageous strategy when it comes to upsets, but that’s certainly not the only reason we’re backing the Ducks.

We also stated these teams enter on opposite trajectories. Starting with Oregon, they enter the NCAA Tournament after winning the Pac-12 Tournament. As for South Carolina, they’re coming off a 31-point loss, so it’s safe to say that they haven’t been as dominant as their women’s team.

Now that you have some background context, let’s dive further into our best Oregon vs. South Carolina prediction.

#11 Oregon vs. #6 South Carolina Expert Picks & Best Bet

There are certain coaches, like Tom Izzo of Michigan State, that simply seem to know how to have their teams ready when it comes to March Madness. It isn’t always the best team that advances, but the team that plays the best in a specific game on a given day.

Oregon head coach Dana Altman needs to start being in those Tom Izzo conversations, as he has led the Ducks to great showings in the NCAA Tournament. In the seven seasons that they have made the dance under Altman, they have won all seven Round of 64 games, and made the Sweet 16 in four of those years.

Furthermore, they made the Elite Eight in two of them, including their first Final Four appearance in 78 years when they made it in 2017. Now, that was some time ago at this point, but it’s also about entering this tournament in good form. Well, the Ducks are doing exactly that after upsetting the #2 Arizona Wildcats en route to winning the Pac-12 Tournament.

That bodes well for Oregon; the last time we saw a team have to win the Pac-12 Tournament to get into the NCAA Tournament was the Oregon State Beavers just a few seasons ago, and what did they do? Make it to the Elite Eight. We already mentioned South Carolina’s crushing 31-point loss less than a week ago, so there’s no denying who is in better form.

The odds suggest an extremely tight matchup, but our best Oregon vs. South Carolina prediction is on the Ducks Money Line (+100 at DraftKings).

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#11 Oregon vs. #6 South Carolina Betting Odds & Lines at DraftKings Sportsbook

Using the prices below, a $10 bet on the best bet from our Oregon vs. South Carolina expert picks of the Ducks Money Line (+100 at DraftKings) profits $10 as long as they pull off the slight upset where as a $12 bet on the Gamecocks ML (-120 at DraftKings) returns $10 of winnings if they win.

Here are the latest Oregon vs. South Carolina odds at DraftKings Sportsbook:

  • Point Spread: Oregon Ducks +1.5 (-110) vs. South Carolina Gamecocks -1.5 (-110)
  • Money Line: Oregon Ducks (+100) vs. South Carolina Gamecocks (-120)
  • Game Total (Over/Under): Over 133 (-112) vs. Under 133 (-108)

#11 Oregon vs. #6 South Carolina Starting Lineups Featuring Jermaine Couisnard & Meechie Johnson Jr.

To wrap things up for our Oregon vs. South Carolina prediction and the matchup overall, here are today’s projected starting lineups:

Oregon Ducks Starting Lineup:

  • Jermaine Couisnard
  • Jackson Shelstad
  • Jadrian Tracey
  • Kwane Evans Jr.
  • N’Faly Dante

South Carolina Gamecocks Starting Lineup:

  • Ta’Lon Cooper
  • Meechie Johnson Jr.
  • Zachary Davis
  • BJ Mack
  • Collin Murray-Boyles

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