Bills' RB Jackson out indefinitely
Wide receiver David Nelson (right knee) was initially diagnosed with a torn ACL and is likely out for the season.
Spiller had a career-best 169 yards against the Jets. Last season, he took over for Jackson as the lead man in Week 11 when Jackson suffered a broken leg at Miami.
Jackson went down with a knee injury in the second quarter at New York Sunday. The team's leading rusher in 2011, Jackson had 934 yards, and third-leading receiver with 39 catches for 442 yards, but missed the final six games.
-- The Sports Xchange