Both players had been previously ruled out for Sunday's game. Will Allen is starting in place of Polamalu, who sprained one of his knees last week against Baltimore.
Shazier has a sprained ankle, suffered during a Week 3 victory at Carolina. Cornerback Ike Taylor, also inactive, was also injured against the Panthers. Linebacker Jason Worilds (abdomen) is active after missing a practice earlier in the week.
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