Fasano is out with a knee injury. Coyle is out with a buttocks injury.
The Chiefs are also down two wide receivers with A.J. Jenkins inactive with a shoulder injury and Donnie Avery still recovering from sports hernia surgery. That means Frankie Hammond Jr. and rookie Albert Wilson figure to get considerable playing time.
Seattle is also missing backup cornerback Marcus Burley, who has a hamstring injury. Strong safety Kam Chancellor is back in the starting lineup after dealing with a groin injury, and nickel cornerback Jeremy Lane is active despite being limited by his own groin injury.
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