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Jan 5, 2025; Glendale, Arizona, USA; San Francisco 49ers defensive end Nick Bosa (97) looks on in the first half against the Arizona Cardinals at State Farm Stadium. Mandatory Credit: Matt Kartozian-Imagn Images

Trades and adjustments the 49ers could make to replace Nick Bosa

Tom Jensen
|
Sep 22, 2025

This is the San Francisco 49ers' biggest concern on defense by far

Parker Hurley
|
Sep 22, 2025

4 changes coming to the 49ers now that Nick Bosa is out for the season

Parker Hurley
|
Sep 22, 2025
49ers defensive end Nick Bosa suffered a season-ending torn ACL.

Nick Bosa Becomes Latest 49ers Star to Get Hurt in Long List of Injuries for Team in 2025

Madison Williams
|
Sep 22, 2025
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Injuries
Jul 24, 2025; Santa Clara, CA, USA; San Francisco 49ers defensive end Nick Bosa (97) awaits his turn during pass rushing drills during the second day of training camp. Mandatory Credit: D. Ross Cameron-Imagn Images

49ers Receive Nightmare Injury Update on Nick Bosa

Jose Sanchez
|
Sep 22, 2025

San Francisco 49ers defensive end Nick Bosa was a candidate to win DPOY.

Nick Bosa Injury Alters 2025 NFL Defensive Player of the Year Odds

Peter Dewey
|
Sep 22, 2025

Bosa will miss the remainder of the 2025 season.

49ers Lose Nick Bosa for Remainder of 2025 Season with Torn ACL

Mike Kadlick
|
Sep 22, 2025

San Francisco 49ers general manager John Lynch, right, talks with head coach Kyle Shanahan.

This player might be the San Francisco 49ers' next superstar

Parker Hurley
|
Sep 22, 2025

San Francisco 49ers general manager John Lynch.

The 49ers made a huge mistake trading this player to the Vikings

Grant Cohn
|
Sep 22, 2025
Sep 21, 2025; Santa Clara, California, USA; San Francisco 49ers running back Christian McCaffrey (23) carries the ball against the Arizona Cardinals during the second half at Levi's Stadium. Mandatory Credit: Cary Edmondson-Imagn Images

Studs and duds from the 49ers' 16-15 win over the Arizona Cardinals

Tom Jensen
|
Sep 22, 2025

Mac Jones enjoyed his second straight win as the 49ers’ temporary starting quarterback.

Five Things We Learned in NFL Week 3: These 49ers Will Survive Injury Onslaught

Gilberto Manzano
|
Sep 22, 2025

Christian McCaffrey is helping to hold down the fort until some of his talented teammates return to the field.

Week 3 NFL Takeaways: 49ers Have a Real Shot to Contend

Albert Breer
|
Sep 22, 2025

San Francisco 49ers head coach Kyle Shanahan.

49ers May Have Solved Their Biggest Problem in Win Over Cardinals

Henry Cheal
|
Sep 22, 2025

Mac Jones threw an interception against the Cardinals and was able to laugh about it after the game.

Mac Jones Was Cackling About His Fourth Quarter Interception During Press Conference

Stephen Douglas
|
Sep 21, 2025

San Francisco 49ers quarterback Mac Jones (10).

49ers 16, Arizona Cardinals 15: Grades

Grant Cohn
|
Sep 21, 2025

Sep 21, 2025; Santa Clara, California, USA; Arizona Cardinals quarterback Kyler Murray (1) is pressured by San Francisco 49ers defensive end Mykel Williams (98) during the second half at Levi's Stadium. Mandatory Credit: Cary Edmondson-Imagn Images

Why Did Cardinals Lose to 49ers? 3 Key Factors

Sam Dehring
|
Sep 21, 2025

Sep 21, 2025; Santa Clara, California, USA; San Francisco 49ers wide receiver Ricky Pearsall (1) makes the catch against the Arizona Cardinals during the second half at Levi's Stadium. Mandatory Credit: Cary Edmondson-Imagn Images

Why Ricky Pearsall is the 49ers' best offensive performer this season

Henry Cheal
|
Sep 21, 2025

The 49ers are undefeated and on the verge of making a serious run

Parker Hurley
|
Sep 21, 2025

Sep 4, 2025; Philadelphia, Pennsylvania, USA; Dallas Cowboys wide receiver CeeDee Lamb (88) warms up prior to the game against the Philadelphia Eagles at Lincoln Financial Field.

CeeDee Lamb, Mike Evans, And 3 Other NFL Week 3 Injury Updates

Gray Deyo
|
Sep 21, 2025
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