Guardians vs. Diamondbacks Prediction, Odds, Probable Pitchers and Prop Bets for Tuesday, Aug. 19

Sean Treppedi | Aug 19, 2025

Geraldo Perdomo has heated up around the bases as of late, so we are looking at his +150 bases prop on Tuesday. / Joe Rondone/The Republic / USA TODAY NETWORK via Imagn Images

The Guardians rode the long ball Monday night, with Brayan Rocchio launching a two-run homer and rookie C.J. Kayfus added a solo shot in a 3-1 win over the Diamondbacks. 

The loss highlighted a rare quiet night for a D-backs lineup that has been steadily climbing in August. 

On the mound, Tanner Bibee (9-9, 4.54 ERA) will look to steady a Cleveland staff that has leaned heavily on him, but he has allowed four or more runs in seven of his last eight starts and carries a 5.59 ERA on the road. 

For Arizona, Eduardo Rodriguez (5-7, 5.40 ERA) gets the ball, and while his surface numbers are poor, his underlying metrics suggest he’s been unlucky. 

Guardians vs. Diamondbacks Odds

Odds via FanDuel Sportsbook

Run Line

• Guardians -1.5 (+158)
• Diamondbacks +1.5 (-192)

Moneyline

• Guardians (+100)
• Diamondbacks (-118)

Total

• Over 8.5 (-118)
• Under 8.5 (-104)

Guardians vs. Diamondbacks How to Watch

• Date: Tuesday, August 19, 2025
• Time: 9:40 p.m. ET
• Venue: Chase Field
• How to Watch (TV): Dbacks.TV, Guardians TV
• Guardians Record: 64-60
• Diamondbacks Record: 60-66

Dodgers vs. Rockies Probable Pitchers

• Guardians: Tanner Bibee (9-9, 4.54 ERA)
• Diamondbacks: Eduardo Rodriguez (5-7, 5.40 ERA)

Guardians vs. Diamondbacks Prop Bet

• Geraldo Perdomo Over 1.5 Total Bases (+150 at FanDuel)

Perdomo has hit safely in 16 of his last 20 home games and is riding a three-game hitting streak entering Tuesday. He’s batting .287 on the year with a sound .388 OBP, ranking seventh in MLB in that category. At Chase Field, Perdomo has been even more reliable, posting strong splits and cashing with a hit in 16 of his last 20 appearances.

Facing a pitcher in Bibee who has been hittable on the road with a 5.59 ERA, Perdomo should be in a good position to extend both his hitting streak and snag a couple bases while he’s at it.

Guardians vs. Diamondbacks Prediction and Pick

The Diamondbacks have generated 130 wRC+ over the last 10 days, and they’ve consistently been one of the league’s better home hitting teams with a .455 SLG on the season. Cleveland, meanwhile, continues to slump offensively, batting just .227 on the year with a measly .299 OBP, and they’ve been especially poor against left-handed pitching.

Bibee has found success in the win column as of late, but I’m favoring Rodriguez’s numbers; has posted a 4.38 xERA and has limited hard contact well, while also owning a 7-0 career record with a 2.51 ERA in nine starts against the Guardians. 

Pick: Diamondbacks (-118 at FanDuel)

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Odds refresh periodically and are subject to change.

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