Penn vs. Illinois Prediction, Odds, Prop Bet for NCAA Tournament 1st Round

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Pennsylvania wasn't the top team in the Ivy League, sitting one step below the likes of Yale and Harvard, but they got hot at the right time en route to winning the Ivy League Tournament, and will now represent the conference in the NCAA Tournament when they take on No. 3 Illinois in the Round of 64.
Illinois lost a heartbreaker to Wisconsin in the Big Ten Tournament, but a deep run in March would erase its missteps in conference competition.
Let's dive into the odds and my best bet for Thursday's matchup.
Pennsylvania vs. Illinois Odds, Spread, and Total
Spread
- Pennsylvania +23.5 (-105)
- Illinois -23.5 (-115)
Moneyline
- Pennsylvania +3000
- Illinois -10000
Total
- OVER 150.5 (-115)
- UNDER 150.5 (-105)
Pennsylvania vs. Illinois How to Watch
- Date: Thursday, March 19
- Game Time: 9:25 pm ET
- Venue: Bon Secours Wellness Arena
- How to Watch (TV): TNT
- Pennsylvania Record: 18-11
- Illinois Record: 24-8
Pennsylvania vs. Illinois Betting Trends
- Pennsylvania is 20-8 ATS this season
- The UNDER is 20-7-1 in Pennsylvania games this season
- Illinois is 18-14 ATS this season
- The UNDER is 18-14 in Illinois games this season
Pennsylvania vs. Illinois Best Prop Bet
- David Mirkovic 15+ Points (-130) via FanDuel
Illinois would be smart to attack Penn where it's at its weakest, which is the interior. Penn ranks 293rd in opponent two-point field goal percentage, allowing teams to shoot 54.4% from two-point range. That could mean big things for David Mirkovic, who is the primary interior shooter for Illinois.
Pennsylvania vs. Illinois Prediction and Pick
Illinois has one of the highest three-point shot rates in the country, ranking 12th in that stat with 50.7% of its shots coming from three-point range. That feeds right into Pennsylvania's defensive strength. The Quakers rank 57th in opponent three-point field goal percentage, allowing teams to shoot just 31.7% from three-point range.
Pennsylvania also plays disciplined basketball, ranking 84th in the country in effective possession ratio.
Illinois will win this game, but the Quakers play the right style of basketball to keep this game within the spread.
Pick: Pennsylvania +23.5 (-105)
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Originally from Nova Scotia, Iain MacMillan is a senior editor covering betting, with a focus on NFL, NHL, and golf. He hosts the Bacon Bets Podcast and has been featured on VSIN, BetQL and Monumental Sports Network. He is a member of the Metropolitan Golf Writers Association and his beloved Falcons and Maple Leafs break his heart on a yearly basis.
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