Puerto Rico vs. Colombia Prediction, Odds, Probable Pitchers for World Baseball Classic

A pair of major-league pitchers take the mound when Puerto Rico and Colombia face off in Pool A action in the 2026 World Baseball Classic.
It’ll be Seth Lugo for host Puerto Rico, and Jose Quintana for Colombia, who is the home team for this matchup.
Puerto Rico went 3-1 in pool play back in 2013 and is favored to win Pool A this time around. Meanwhile, Colombia is hanging in the shadows with +550 odds to take the pool despite just one win in four games in 2023.
Here are the odds, probable pitchers, and predictions for Puerto Rico vs. Colombia on Friday evening.
Puerto Rico vs. Colombia Odds & Run Line
Odds via DraftKings Sportsbook
Moneyline
- Puerto Rico -425
- Colombia +310
Run Line
- Puerto Rico -3.5 (-110)
- Colombia +3.5 (-115)
Total
- 9.5 (Over -110/Under -110)
Puerto Rico vs. Colombia Probable Pitchers
- Puerto Rico: Seth Lugo
- Colombia: Jose Quintana
Puerto Rico vs. Colombia How to Watch
- Date: Friday, March 6
- Time: 6:00 p.m. ET
- Venue: Hiram Bithorn Stadium - San Juan, PR
- How to Watch (TV): FS1, Fox Deportes
Puerto Rico vs. Colombia Prediction and Pick
Puerto Rico isn’t one of the big dogs in this tournament, but they’re firmly in the group of teams that could surprise some people. It has a few MLB players, including Heliot Ramos and Nolan Arenado, and Lugo isn’t a bad starter at the top of the rotation.
Colombia counters with Quintana and Seattle prospect Michael Arroyo leading the way offensively. It also has a few familiar names, like Harold Ramirez and Jorge Alfaro
Lugo has refined his game in recent years, posting a 3.50 ERA in the last three seasons since becoming a starter. Quintana has also been able to stick around with solid numbers even in his mid-30s, posting a 3.96 ERA for Milwaukee last season.
In a matchup between two solid MLB starters, I can only look to the UNDER in this one before the bats get going.
Pick: UNDER 9.5 (-110)
Odds refresh periodically and are subject to change.
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Ryan is a sports betting writer at Sports Illustrated. He has experience working for NHL.com, NBC Sports, Covers, and more throughout his decade in the industry. As a Philadelphia native, he understands the passion and pain that come with being a sports fan.
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