Rangers vs. Angels Prediction, Odds, Probable Pitchers, Prop Bets for Friday, May 22

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The Texas Rangers are looking to get back up to .500 as they close out their road trip with a three-game set against the Los Angeles Angels this weekend.
The Rangers scored one run in their first two games on this trip, but then took the finale in Houston and won their final two games in Colorado as well.
On the other hand, the Angels lost the final three games of a four-game set against the A’s to fall to 17-34 on the season.
Here are the odds, probable pitchers, and predictions for Rangers vs. Angels on Friday, May 22.
Rangers vs. Angels Odds, Run Line and Total
Odds via DraftKings Sportsbook
Run Line
- Rangers -1.5 (-101)
- Angels +1.5 (-120)
Moneyline
- Rangers -168
- Angels +139
Total
- 7.5(Over -113/Under -107)
Rangers vs. Angels Probable Pitchers
- Rangers: Jacob deGrom (3-3, 3.02 ERA)
- Angels: Grayson Rodriguez (0-1, 17.18 ERA)
Jacob deGrom has been up and down recently. He’s allowed four runs or more in two of his last three starts, but threw seven shutout innings with 10 strikeouts against the Cubs in between.
Grayson Rodriguez really struggled in his first start since 2024. He allowed seven runs on as many hits with four walks in 3.2 innings against the Dodgers in his Angels debut.
Rangers vs. Angels How to Watch
- Date: Friday, May 22
- Time: 9:38 p.m. ET
- Venue: Angels Stadium
- How to Watch (TV): CWSS, ABTV
- Rangers record: 24-25
- Angels record: 17-34
Rangers vs. Angels Best MLB Prop Bets
Rangers Best MLB Prop Bet
- Jake Burger OVER 1.5 Hits + Runs + RBIs (-103)
Jake Burger has been beefing up his stats during a recent hot streak. Since seeing his average drop to a season-low .204 on May 11, he’s gone 13 for 29 (.448) with 6 runs scored and 12 RBI.
Burger has gone OVER 1.5 HRR in five straight games and seven of his last eight while moving up the Rangers’ batting order. He should stay hot against a struggling Angels team, and he’s 1 for 2 with a home run against Rodriguez in his career.
Rangers vs. Angels Prediction and Pick
Fading the Angels has been very profitable recently, and I’m not going to stop now.
The Rangers have a huge pitching advantage with deGrom against Rodriguez, and the Angels’ offense has been dreadful recently.
I’ll take the Rangers on the moneyline as my best bet, but the -1.5 (-101) is probably worth it to cut down the juice.
Pick: Rangers -168
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Ryan is a sports betting writer at Sports Illustrated. He has experience working for NHL.com, NBC Sports, Covers, and more throughout his decade in the industry. As a Philadelphia native, he understands the passion and pain that come with being a sports fan.
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