Spurs vs. Pistons Prediction, Odds and Best NBA Prop Bets for Tuesday, March 25

If the San Antonio Spurs are supposed to be tanking, nobody told their young core.

San Antonio has won five of its last 10 games, including three in a row, to move to 31-39 in the 2024-25 season. Even with Victor Wembanyama and De’Aaron Fox out for the season, the Spurs have been able to be competitive with Stephon Castel, Devin Vassell and others leading the way.

On Tuesday, the Spurs find themselves as road underdogs against the Detroit Pistons, who have gone from a 14-win team to a playoff team in just one season.

All-Star guard Cade Cunningham missed the Pistons’ last game on Sunday against the New Orleans Pelicans, but he’s listed as questionable on Tuesday.

Here’s a full breakdown of this matchup, including the latest betting odds, players to bet on in the prop market, and my prediction.

Spurs vs. Pistons Odds, Spread and Total

Odds via DraftKings Sportsbook.

Spread

Spurs +10.5 (-115)
Pistons -10.5 (-105)

Moneyline

Spurs: +340
Pistons: -440

Total

235 (Over -112/Under -108)

Spurs vs. Pistons How to Watch

Date: Tuesday, March 25
Time: 7:00 p.m. EST
Venue: Little Caesars Arena
How to Watch (TV): FanDuel Sports Network (Local), NBA League Pass
Spurs record: 31-39
Pistons record: 40-32

Spurs vs. Pistons Injury Reports

Spurs Injury Report

Charles Bassey – out
Stephon Castle – questionable
Victor Wembanyama – out
David Duke Jr. – out
Riley Minix – out
Harrison Ingram – out
De’Aaron Fox – out

Pistons Injury Report

Cade Cunningham – questionable
Tim Hardaway Jr. – questionable
Ron Harper Jr. – out
Jaden Ivey – out
Daniss Jenkins – out
Tolu Smith – out
Bobi Klintman – out

Spurs vs. Pistons Best NBA Prop Bets

San Antonio Spurs Best NBA Prop Bet

Stephon Castle UNDER 20.5 Points (-120)

With Castle listed as questionable on Tuesday, he’s a fade candidate in the prop market against a stout Detroit defense.

Castle has failed to clear 20.5 points in seven of his last 11 games, averaging 18.5 points per game over that stretch. While the rookie guard has had an expanded role with Fox and Wemby out for the season, this number is a little high for my liking since he is still a below-average shooter (42.8 percent from the field, 28.7 percent from 3). Castle had 12 points off the bench in his last game against these Pistons.

Detroit Pistons Best NBA Prop Bet

Cade Cunningham OVER 9.5 Assists (-105)

Earlier this season, Cunningham dropped 12 dimes against the Spurs, who are just 23rd in the NBA in opponent assists per game.

Cunningham is averaging over nine assists per game this season, and he could be worth a short in this market with San Antonio playing a bunch of high-scoring games as of late. Cade is averaging 15.4 potential assists per game this season, giving him a terrific floor when it comes to this prop.

Spurs vs. Pistons Prediction and Pick

With Cade Cunningham’s status up in the air, I lean with the Spurs to stay hot and cover in this matchup.

San Antonio has won three straight and five of its last 10, posting the No. 15 net rating in the NBA over that stretch.

Meanwhile, the Pistons have struggled when favored at home all season long, going just 6-11 against the spread. Detroit may end up winning this game – like it did against New Orleans on Sunday – but asking it to cover a double-digit spread with Cunningham potentially out is a tall task.

As it is, the Pistons don’t have a true No. 1 option that can step up behind Cade, and the Spurs have the No. 1 offensive rating in the NBA over their last 10 games.

If San Antonio can keep scoring at a high rate, it’ll at least hang around in this matchup as a double-digit underdog.

Pick: Spurs +10.5 (-115 at DraftKings)

Odds refresh periodically and are subject to change.

If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.

Find Peter Dewey's NBA betting record here (futures included). You can also follow my daily plays on BetStamp here.

Are you new to DraftKings? Sign up today and place a $5 bet to earn a guaranteed $150 in bonus bets. Win or lose, DraftKings will issue six $25 bonus bets instantly.