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Tigers vs. Padres Prediction, Odds, Probable Pitchers, Prop Bets for Friday, March 27

Xander Bogaerts and the Padres are home favorites against the Tigers.
Xander Bogaerts and the Padres are home favorites against the Tigers.
Xander Bogaerts and the Padres are home favorites against the Tigers. | David Frerker-Imagn Images

The Detroit Tigers got off the mark with an 8-2 win in San Diego on Thursday night. They put up four runs in the first inning and never looked back to start the season 1-0.

Framber Valdez will make his Tigers debut and follow Tarik Skubal in the Detroit rotation, with Michael King opposing him for San Diego.

Here are the odds, probable pitchers, and predictions for Tigers vs. Padres on Friday, March 27.

Tigers vs. Padres Odds, Run Line and Total

Odds via DraftKings Sportsbook

Run Line

  • Tigers -1.5 (+162)
  • Padres +1.5 (-198)

Moneyline

  • Tigers +104
  • Padres -126

Total

  • 7.5 (Over -105/Under -115)

Tigers vs. Padres Probable Pitchers

  • Tigers: Framber Valdez (13-11, 3.66 ERA in 2025)
  • Padres: Michael King (5-3, 3.44 ERA in 2025)

Tigers vs. Padres How to Watch

  • Date: Friday, March 27
  • Time: 9:40 p.m. ET
  • Venue: Petco Park
  • How to Watch (TV): DSN, SDPA
  • Tigers record: 1-0
  • Padres record: 0-1

Tigers vs. Padres Best MLB Prop Bets

Padres Best MLB Prop Bet

  • Xander Bogaerts OVER 1.5 Hits + Runs + RBIs (-111)

Xander Bogaerts started the season strong with two hits, including an RBI double, on Thursday. 

He hit in the two hole between Fernando Tatis Jr. and Manny Machado in that one, and he should be back there tonight against another southpaw. The veteran shortstop is 4 for 14 with a double against Valdez in his career.

Bogaerts has been much better vs. LHP (.302 average, .840 OPS) than vs. RHP (.282, .781) in his career, and that continued last season. He also hit .272 at home and .254 on the road last year.

Tigers vs. Padres Prediction and Pick

Nick Pivetta didn’t give the Padres much of a chance yesterday, walking in a run to start off a four-run first inning for Detroit. I don’t see King doing that again tonight.

San Diego was an impressive 52-29 at home last season, while Detroit went 41-40 on the road despite finishing 87-75. 

I’ll back the Padres to get their first win of the season on Friday night.

Pick: Padres moneyline (-126)


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Ryan Gilbert
RYAN GILBERT

Ryan is a sports betting writer at Sports Illustrated. He has experience working for NHL.com, NBC Sports, Covers, and more throughout his decade in the industry. As a Philadelphia native, he understands the passion and pain that come with being a sports fan.

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